臨床製剤学講座
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研究実績 論文

  • 231. Preparation and Characterization of Orally Fast-Disintegrating Mini-Tablets Containing Diphenhydramine Hydrochloride and Aspartic or Glutamic Acid as an Umami Amino Acid
    Ohkawa K., Nishikawa H., Kojima H., Okuno T., Uno R., Yoshida M., Uchida T.
    Pharmacology & Pharmacy 12 (12): 283-292 (2021)
  • 230.Targeted Delivery of Miconazole Employing LL37 Fragment Mutant Peptide CKR12-Poly (Lactic-Co-Glycolic) Acid Polymeric Micelles
    Mori T., Yoshida M., Hazekawa M., Ishibashi D., Hatanaka Y., Kakehashi R., Nakagawa M., Nagao T., Yoshii M., Kojima H., Uno R., Uchida T.
    International Journal of Molecular Sciences 22 (21): 12056 (2021)
  • 229. pH特性曲線の理論式を用いた新規pH算出法
    浅原慶一、吉田都、内田享弘
    日本注射薬臨床情報学会誌No.9 (2021)
  • 228. Preparation of siRNA-PLGA/Fab'-PLGA mixed micellar system with target cell-specific recognition
    Hazekawa M., Nishinakagawa T., Mori T., Yoshida M., Uchida T., Ishibashi D.
    Scientific Reports 11(1): 16789 (2021)
  • 227. Enhancing the anticancer efficacy of a LL-37 peptide fragment analog using peptide-linked PLGA conjugate micelles in tumor cells
    Mori T., Hazekawa M., Yoshida M., Nishinakagawa T., Uchida T., Ishibashi D.
    International Journal of Pharmaceutics 606: 120891 (2021)
  • 226. Antimicrobial Activities of LL-37 Fragment Mutant-Poly (Lactic-Co-Glycolic) Acid Conjugate against Staphylococcus aureus, Escherichia coli, and Candida albicans
    Mori T., Yoshida M., Hazekawa M., Ishibashi D., Hatanaka Y., Nagao T., Kakehashi R., Kojima H., Uno R., Ozeki M., Kawasaki I., Yamashita T., Nishikawa J., Uchida T.
    International Journal of Molecular Sciences 22 (10): 5097 (2021)
  • 225. A New Bitterness Evaluation Index Obtained Using the Taste Sensor for 48 Active Pharmaceutical Ingredients of Pediatric Medicines
    Kojima H., Kurihara T., Yoshida M., Haraguchi T., Nishikawa H., Ikegami S., Okuno T., Yamashita T., Nishikawa J., Tsujino H., Arisawa M., Habara M., Ikezaki H., Uchida T.
    Chem. Pharm. Bull. 69 (6): 537-547 (2021)
  • 224. Preparation of Solifenacin Succinate Functional Particles Embedded in a Gelling-Swelling Layer (PEGS) and Their Formulation in Orally Disintegrating Tablets
    Ijitsu S., Hoashi Y., Hori K., Okimoto K., Kai T., Yoshida M., Uchida T.
    Chem. Pharm. Bull. 69 (5): 456-463 (2021)
  • 223. Preparation of Novel Functional Drug Particles Embedded in a Gelling-Swelling Layer (PEGS) for Taste Masking and Subsequent Rapid Drug Release
    Ijitsu S., Hoashi Y., Hori K., Okimoto K., Kai T., Yoshida M., Uchida T.
    Chem. Pharm. Bull. 69 (4): 383-390 (2021)
  • 222. Evaluation of the Palatability of Dry Syrups and the Bitterness Intensities of Dry Syrups Mixed with Various Beverages
    Kurihara T., Kojima H., Yoshida M., Oshio M., Kunikata R., Nishikawa H., Uchida T.
    Pharmacology & Pharmacy 12 (2): 43-54 (2021)
  • 221. YS-1301の血管新生作用と実用化のための再生医療製剤の開発
    櫨川舞、内田享弘
    BIO INDUSTRY 37 (8): 91-99 (2020)
  • 220. 経口抗がん薬の経管投与における曝露対策の評価
    福永千佳子、河野えみ子、鍛治谷玲子、三箇山宏樹、關壽人、北出浩章、馬場綾、相地知子、西辻知恵美、吉田都、内田享弘
    日本注射薬臨床情報学会誌No.8 (2020)
  • 219. Development of Taste Sensor to Detect Non-Charged Bitter Substances .
    Yoshimatsu J., Toko K., Tahara Y., Ishida M., Habara M., Ikezaki H., Kojima H., Ikegami S., Yoshida M., Uchida T.
    Sensors 20 (12): 3455 (2020)
  • 218. Observational study to determine the optimal dose of daptomycin based on pharmacokinetic/pharmacodynamic analysis.
    Yamada T., Ooi Y., Oda K., Shibata Y., Kawanishi F., Suzuki K., Nishihara M., Nakano T., Yoshida M., Uchida T., Katsumata T., Ukimura A.
    J Infect Chemother. 26 (4): 379-384 (2020)
  • 217. Bitterness-Suppressing Effect of Umami Dipeptides and Their Constituent Amino Acids on Diphenhydramine: Evaluation by Gustatory Sensation and Taste Sensor Testing.
    Okuno T., Morimoto S., Nishikawa H., Haraguchi T., Kojima H., Tsujino H., Arisawa M., Yamashita T., Nishikawa J., Yoshida M., Habara M., Ikezaki H., Uchida T.
    Chem Pharm Bull. 68 (3): 234-243 (2020)
  • 216. Preparation and Evaluation of Poly-γ-glutamic Acid Hydrogel Mixtures with Amlodipine Besylate: Effect on Ease of Swallowing and Taste Masking.
    Kojima H., Haraguchi T., Ikegami S., Nishikawa H., Yoshida M., Ozeki M., Kawasaki I., Uchida T.
    Chem Pharm Bull. 67 (12): 1284-1292 (2019)
  • 215. The Relationship between Bitter Taste Sensor Response and Physicochemical Properties of 47 Pediatric Medicines and Their Biopharmaceutics Classification.
    Haraguchi T., Okuno T., Nishikawa H., Kojima H., Ikegami S., Yoshida M., Habara M., Ikezaki H., Uchida T.
    Chem Pharm Bull. 67 (12): 1271-1277 (2019)
  • 214. Preparation and Evaluation of Poly-γ-Glutamic Acid Hydrogel Mixtures with Basic Drugs or Acidic Drugs: Effect on Ease of Swallowing and Taste Masking.
    Kojima H., Ikegami S., Nakamura S., Nishikawa H., Haraguchi T., Yoshida M., Ozeki M., Kawasaki I., Uchida T.
    Pharmacology & Pharmacy 10 (10): 427-444 (2019)
  • 213. A new strategy for taste masking on bitter drug by other combined drug in fixed-dose combination: bitterness of Amlodipine besylate could be masked efficiently by Valsartan.
    Kojima H., Nakamura S., Haraguchi T., Yoshida M., Habara M., Ikezaki H., Uchida T.
    J Pharm Pharmacol. 71(9): 1384-1392 (2019)
  • 212. Hydrogen sulfide donating ent-kaurane and spirolactone-type 6,7-seco-ent-kaurane derivatives: Design, synthesis and antiproliferative properties.
    Li H., Gao X., Huang X., Wang X., Xu S., Uchida T., Gao M., Xu J., Hua H., Li D.
    Eur J Med Chem. 178: 446-457 (2019)
  • 211. 経口製剤・注射剤に関する臨床製剤学的評価
    内田享弘
    医療薬学 45(5): 241-253 (2019)
  • 210. Bitterness-Masking Effects of Different Beverages on Zopiclone and Eszopiclone Tablets.
    Yoshida M., Kojima H., Uda A., Haraguchi T., Ozeki M., Kawasaki I., Yamamoto K., Yano I., Hirai M., Uchida T.
    Chem Pharm Bull. 67(5): 404-409 (2019)
  • 209. Preparation and Characterization of Itraconazole- or Miconazole-Loaded PLGA Microspheres.
    Matsuura K., Kojima H., Haraguchi T., Yoshida M., Suzuki S., Suzuki T., Ando S., Uchida T.
    Chem Pharm Bull. 67(2): 106-111 (2019)
  • 208. Solubility improvement of Benexate through salt formation using artificial sweetener.
    Dwichandra P., Umeda D., Fujita E., Haraguchi T., Uchida T., Yonemochi E., Uekusa H.
    Pharmaceutics. 10(2): 64 (2018)
  • 207. The utility of the artificial taste sensor in evaluating the bitterness of drugs: correlation with responses of human TASTE2 receptors (hTAS2Rs).
    Haraguchi T, Uchida T, Yoshida M, Kojima H, Habara M, Ikezaki H.
    Chem Pharm Bull. 66(1): 71-77 (2018)
  • 206. Preparation and evaluation of physicochemical properties of Isosorbide gel composed of xanthan gum, locust bean gum and agar for improving the patient’s adherence.
    Kawano Y, Kiuchi H, Haraguchi T, Yoshida M, Uchida T, Hanawa T.
    International Journal of Medicine and Pharmacy. 5(1): 18-32 (2017)
  • 205. Nitric oxide-releasing derivatives of brefeldin A as potent and highly selective anticancer agents.
    Tian K, Xu F, Gao X, Han T, Li J, Pan H, Zang L, Li D, Li Z, Uchida T, Gao M, Hua H.
    Eur. J. Med. Chem. 136: 131-143 (2017)
  • 204. Effect of self-healing encapsulation on the initial burst release from PLGA microspheres containing a long-acting prostasyclin agonist, ONO-1301.
    Hazekawa M, Kojima H, Haraguchi T, Yoshida M, Uchida T.
    Chem. Pharm. Bull. 65(7): 653-659 (2017)
  • 203. Suppression in bitterness intensity of bitter basic drug by chlorogenic acid.
    Shiraishi S, Haraguchi T, Nakamura S, Kojima H, Kawasaki I, Yoshida M, Uchida T.
    Chem. Pharm. Bull. 65(2): 151-156 (2017)
  • 202. Taste-masking effect of Chlorogenic acid (CGA) on bitter drugs evaluated by taste sensor and surface plasmon resonance on the basis of CGA-drug interactions.
    Shiraishi S, Haraguchi T, Nakamura S, Dahong Li, Kojima H, Yoshida M, Uchida T.
    Chem. Pharm. Bull. 65(2): 127-133 (2017)
  • 201. Comparison of the adsorption of original and biosimilar preparations of filgrastim on infusion sets and the inhibition of adsorption by polysorbate 80.
    Tange M, Matsumoto A, Yoshida M, Kojima H, Haraguchi T, Uchida T.
    Chem. Pharm. Bull. 65(1): 36-41 (2017)
  • 200. ゾピクロン錠とエスゾピクロン錠の苦味比較
    宇田篤史、吉田都、原口珠実、櫨川舞、水本篤志、山本和宏、平野剛、内田享弘、平井みどり
    日本病院薬剤師会雑誌 52(5): 529-532 (2016)
  • 199. Quantitative prediction of bitterness masking effect of high-potency sweetners using taste sensor.
    Wu.X, Onitake H, Haraguchi T, Tahara Y, Yatabe R, Yoshida M, Uchida T, Ikezaki H, Toko K.
    Sens. Actuators B. 235: 11-17 (2016)
  • 198. Usefulness and limitations of taste sensors in the evaluation of palatability and taste-masking in oral dosage forms.
    Haraguchi T, Yoshida M, Kojima H, Uchida T.
    Asian J Pharm. Sci. 11(4): 479-485 (2016)
  • 197. Consideration of dosage regimen for meropenem in mixed infusions containing L-cysteine and/or SBS.
    Shino N, Nomura Y, Yoshida M, Uchida T.
    J. Drug. Inter. Res. 39(3): 145-156 (2016)
  • 196. The Role of an Impurity in Ceftriaxone Sodium Preparation for Injection in Determining Compatibility with Calcium-Containing Solutions.
    Tange M, Yoshida M, Nakai Y, Uchida T
    Chem Pharm Bull, 64(3), 207-214 (2016)
  • 195. The Ability of foods/drinks to reduce the bitterness intensity of topiramate as determined by taste sensor analysis.
    Haraguchi T, Uchida T, Hazekawa M, Yoshida M, Nakashima M, Sanda H, Hase T, Tomoda Y
    Chem Pharm Bull, 64(1), 14-20 (2016)
  • 194. Development and Assessment of a Nomogram to Propose the Initial Dosage Regimen of a Meropenem Infusion Based on Serum Creatinine and Age Using a Monte Carlo Simulation.
    Shino N, Uchida T, Yoshida M, Nomura Y.
    Chem Pharm Bull, 63(12), 986-991 (2015)
  • 193. Development and evaluation of an optimized dosage regimen for carbapenems in elderly patients based on PK?PD parameters and Monte Carlo simulations
    Shino N, Uchida T, Yoshida M, Nomura Y
    The Japanese Journal of Nephrology and Pharmacotherapy, 4, 21-30 (2015)
  • 192. 味覚センサを用いて医薬品の味を科学する
    吉田都、内田享弘
    ファルマシア 51(2), 130-134 (2015)
  • 191. Multiple linear regression analysis indicates association of P-glycoprotein substrate or inhibitor character with bitterness intensity, measured with a sensor
    Yano K, Mita S, Morimoto K, Haraguchi T, Arakawa H, Yoshida M, Yamashita F, Uchida T, Ogihara T
    J. Pharm. Sci. 104(9), 2789-2794 (2015)
  • 190. Evaluation of the palatability in 10 different famotidine orally disintegrating tablets by combination of disintegration device and taste sensor
    Yoshida M, Hazekawa M, Haraguchi T, Uchida T.
    Drug. Dev. Ind. Pharm. 41(8), 1387-1392 (2015)
  • 189. Prediction of the stability of meropenem in intravenous mixtures
    Takasu Y, Yoshida M, Tange M, Asahara K, Uchida T.
    Chem. Pharm. Bull. 63(4), 248-254 (2015)
  • 188. The bitterness intensity of pharmaceutical ingredients determined by taste sensor
    Uchida T, Yoshida M.
    IEEJ Transactions on sensors and micromachines, 135(2), 46-50 (2015)
  • 187. 製剤開発におけるトレードオフ(overview)
    内田享弘
    YAKUGAKU ZASSHI, 135(2), 221-227 (2015)
  • 186. 患者指向と有効性のトレードオフをイノベーションで克服した次世代型製剤
    内田享弘、並木徳之
    YAKUGAKU ZASSHI, 135(2), 219-220 (2015)
  • 185. 味覚センサを用いたガストログラフインの味評価と飲料混合時の味変化の予測
    内田享弘、原口珠実、吉田都
    Progress in Medicine, 34(12), 2195-2200 (2014)
  • 184. リドカインうがい液が味覚に与える影響
    向井淳治、徳山絵生、宮武望、小野原未由来、豊田和、原口珠実、内田享弘
    癌と化学療法, 41(11), 1413-1416. (2014)
  • 183. Evaluation of ebastine-loaded orally disintegrating tablets using new apparatus of detecting disintegration time and e-tongue system
    Haraguchi T, Yoshida M, Uchida T
    J. Drug Del. Sci. Tech. 24(6), 684-688 (2014)
  • 182. Bitterness evaluation of acidic pharmaceutical substances (NSAIDs) using a taste sensor
    Yoshida M, Haraguchi T, Uchida T
    Chem. Pharm. Bull. 62(12), 1252-1258 (2014)
  • 181. The angiogenic effect of ONO-1301, a novel long-acting prostacyclin agonist loaded in PLGA microspheres prepared using different molecular weights of PLGA, in a murine sponge model
    Hazekawa M, Morihata K, Yoshida M, Sakai Y, Uchida T.
    Drug. Dev. Ind. Pharm. 40(11), 1435-1442 (2014)
  • 180. Comprehensive evaluation of palatability for commercial medicine by taste sensing system
    Uchida T.
    Yakugaku Zasshi, 134(3), 317-323 (2014)
  • 179. Recent topic of kansei biosensors on taste and odor sensing systems
    Uchida T, Toko K.
    Yakugaku Zasshi, 134(3), 305-306 (2014)
  • 178. 人工唾液を用いた市販ドネペジル塩酸塩口腔内崩壊錠の崩壊性評価U
    櫨川舞、原口珠実、吉田都、内田享弘
    医学と薬学, 71(3), 437-447 (2014)
  • 177. Prediction of the stability of Octoreotide in a mixed infusion
    Takasu Y, Yoshida M, Simizu K, Asahara K, Tange M, Uchida T.
    Chem. Pharm. Bull. 62(4), 1-6 (2014)
  • 176. A novel long-acting prostacyclin agonist (ONO-1301) with an angiogenic effect: promoting synthesis of hepatocyte growth factor and increasing cyclic AMP concentration via IP-receptor signaling
    Uchida T, Hazekawa M, Yoshida M, Matsumoto K, Sakai Y.
    J Pharmacol Sci. 123, 392-401 (2013)
  • 175. 味覚センサを用いたムコスタ® 点眼液UD2%に含有されるレバミピドの苦味評価と飲食物による苦味抑制評価
    原口珠実、宮崎愛里、吉田都、内田享弘
    あたらしい眼科, 30(11), 1619-1622 (2013)
  • 174. Comparison of the dissolution rate of ceftriaxone sodium preparations for injection
    Tange M, Hattori Y, Otsuka M, Yoshida M, Haginaka J, Uchida T
    Chem. Pharm. Bull. 61(11), 1121-1129 (2013)
  • 173. Evaluation of palatability of 10 commercial amlodipine orally disintegrating tablets by gustatory sensation testing, OD-mate as a new disintegration apparatus and the artificial taste sensor
    Uchida T, Yoshida M, Hazekawa M, Haraguchi T, Furuno H, Teraoka M, Ikezaki H
    J. Pharm. Pharmacol. 65(9), 1312-1320 (2013)
  • 172. 女性医療専門職(薬剤師)を対象とした再就職支援のためのニーズ調査
    吉田 都、繻エ 晶子、豊原 朋子、片岡 和三郎、岡村 昇、三木 知博、笠井 眞二、政田 啓子、木下 健司、村田 成範、中林 利克、篠塚 和正、高橋 幸一、市川 厚、上村 直樹、後藤 惠子、宮崎 智、波多江 崇、東海林 徹、内田 享弘.
    医薬品相互作用研究, 37(1), 9-16 (2013)
  • 171. SD法を用いた市販アンブロキソール錠10製剤の服用性評価
    櫨川舞、吉田都、内田享弘
    新薬と臨牀, 62(8), 1389-1397 (2013)
  • 170. 人工唾液を用いた市販ドネペジル塩酸塩口腔内崩壊錠の崩壊性評価
    櫨川舞、原口珠実、六戸部真里、吉田都、内田享弘
    医学と薬学, 69(6), 929-938 (2013)
  • 169. 高感度型味覚センサの開発と製剤設計への応用
    内田享弘.
    薬剤学, 73(4), 239-245 (2013)
  • 168. Bitterness evaluation of intact and crushed Vesicare® orally disintegrating tablets using taste sensors
    Haraguchi T, Miyazaki A, Yoshida M, Uchida T.
    J. Pharm. Pharmacol, 65, 980-987(2013)
  • 167. Prediction of compatibility between ozagrel sodium preparation for injection and calcium on the basis of the solubility product
    Tange M, Yoshida M, Hazekawa M, Haraguchi T, Nakai Y, Uchida T.
    Chem. Pharm. Bull, 61(5), 567-571(2013)
  • 166. Effect of antioxidants on the stability of ONO-1301, a novel long-acting prostacyclin agonist, loaded in PLGA microspheres
    Uchida T, Hazekawa M, Morisaki T, Yoshida M, Sakai Y.
    J. Microencapsul, 30(3), 245-256(2013)
  • 165. Evaluation of the odor of Aminoleban® EN, taste-masked with flavoured powders, by human and electronic noses
    Haraguchi T, Yoshida M, Uchida T.
    J. Pharm. Pharmacol, 65, 503-511(2013)
  • 164. Bitterness prediction of H1-antihistamines and prediction of masking effects of artificial sweeteners using an electronic tongue
    Ito M, Ikehama K, Yoshida K, Haraguchi T, Yoshida M, Wada K, Uchida T.
    Int. J. Pharm, 441(1-2), 121-127(2013)
  • 163. Quantitative evaluation of bitterness of H1-receptor antagonists and masking effect of acesulfame potassium, an artificial sweetener, using a taste sensor
    Ito M, Wada K, Yoshida M, Hazekawa M, Abe K, Chen R, Habara M, Ikezaki H, Uchida T.
    Sensor and Materials, 25(1), 17-30 (2013)
  • 162. Prediction of the stability of imipenem in intravenous mixtures
    Yoshida M, Takasu Y, Shimizu K, Asahara K, Uchida T.
    Chem. Pharm. Bull, 61(1), 1-7 (2013)
  • 161. 分岐鎖アミノ酸を対象とした苦味及び苦味抑制効果の味覚センサによる評価手法の検討
    大杉啓悟、田原祐助、秋冨博紀、安浦雅人、小林義和、中野美智江、池崎秀和、原口珠実、内田享弘、都甲潔
    日本味と匂学会誌, 19(3), 421-424 (2012)
  • 160. アンブロキソールドライシロップまたはカルボシステインドライシロップとクラリスロマイシンドライシロップ同時服用時の苦味強度の定量的評価
    内田 享弘、櫨川 舞
    Prog. Med., 32, 2245-2250 (2012)
  • 159. 味覚センサを用いた医薬品の味評価
    内田享弘
    日本味と匂学会誌, 19(2), 13-18 (2012)
  • 158. Factors affecting the bitterness intensities of ten commercial formulations of ambroxol
    Uchida T, Sugino Y, Hazekawa M, Yoshida M, Haraguchi T.
    Chem. Pharm. Bull, 60(8), 949-954 (2012)
  • 157. 注射剤の配合変化による微粒子析出について―フェニトインナトリウム注およびセフトリアキソンナトリウム注の事例―
    内田享弘、中井由佳、丹下美緒、吉田都
    日本注射薬臨床情報学会会誌, 1, 21-31 (2012)
  • 156. Comparison between original and generic versions of ceftriaxone sodium preparation for injection: compatibility with calcium-containing product
    Tange M, Yoshida M, Nakai Y, Uchida T.
    Chem. Pharm. Bull, 60(4), 429-434 (2012)
  • 155. Single injection of ONO-1301-loaded PLGA microspheres directly after ischemia reduces ischemic damage in rats subjected to middle cerebral artery occlusion
    Hazekawa M, Sakai Y, Yoshida M, Haraguchi T, Uchida T.
    J. Pharm. Pharmacol, 64, 353-359 (2012)
  • 154. The effect of treatment with a sustained-release prostacyclin analog (ONO-1301-loaded PLGA microspheres) on short-term memory impairment in rats with
    transient global cerebral ischemia
    Hazekawa M, Sakai Y, Yoshida M, Haraguchi T, Uchida T.
    J. Microencapsul, 29(3), 211-218 (2012)
  • 153. 口腔内崩壊錠の臨床評価
    内田享弘, 原田努.
    J Pharm Tech Japan, 28(2), 245-251 (2012)
  • 152. Bitterness evaluation of H1-receptor antagonists using a taste sensor
    Ito M, Yoshida M, Kobayashi Y, Hiraoka M, Ikezaki H, Uchida T.
    Sensors and Materials, 23(8), 483-492 (2011)
  • 151. クレメジン®細粒・後発品の製剤学的特性と服用性の評価
    内田享弘, 吉田都
    新薬と臨牀 J. New Rem.& Clin, 60(8), 1548-1553 (2011)
  • 150. Neuroprotective effect of a prostacyclin agonist (ONO-1301) with thromboxane synthase inhibitory activity in rats subjected to cerebral ischemia
    Hazekawa M, Sakai Y, Yoshida M, Haraguchi T, Uchida T.
    Pharmacol. & Pharm, 2(4), 306-314 (2011)
  • 149. Synergistic effect of sour taste and low temperature in suppression the bitterness of Aminoleban(R) EN.
    Haraguchi T, Yoshida M, Hazekawa M, Uchida T.
    Chem. Pharm. Bull, 59 (5), 536-540 (2011)
  • 148. Influence of Swallowing Aids on the Adsorption and Palatability of Kremezin(R)
    Yoshida M, Hazekawa M, Haraguchi T, Uchida T.
    Chem. Pharm. Bull, 59 (4), 434-437 (2011)
  • 147. Preparation of ONO-1301-loaded PLGA microspheres and their effect on nerve conduction velocity
    Hazekawa M, Sakai Y, Yoshida M, Haraguchi T, Morisaki T, Uchida T.
    J. Pharm. Pharmacol, 63, 362-368 (2011)
  • 146. 「ヤマブシタケ子実体」食品によるマウスの脳梗塞改善作用
    片岡愛子, 櫨川 舞, 入江圭一, 秋武義治, 中野貴文, 早川和秀, 三島健一, 三島健司, 吉田 都, 藤原稔大, 内田享弘, 小松靖弘, 岩崎克典, 藤原道弘
    機能性食品と薬理栄養, 6(5), 281-287 (2011)
  • 145. 第一期長期実務実習を振り返って(実習の成果と課題)
    内田享弘
    薬事新報, 2650, 39-44 (2010)
  • 144. 武庫川女子大学薬学研究科昼夜開講(社会人)大学院におけるPhaSeal(R) systemを用いた模擬抗がん剤調製実習プログラム
    櫨川舞, 原口珠実, 岡田祥恵, 吉田都, 内田享弘
    医療薬学, 36(5), 328-334 (2010)
  • 143. クラリスロマイシンドライシロップ製剤の酸性スポーツ飲料併用時およびムコダイン(R)DS併用時の苦味予測
    櫨川舞, 盛崎友美, 藤井香保里, 丹下美緒, 原口珠実, 吉田都, 内田享弘
    医療薬学, 36(4), 262-269 (2010)
  • 142. Molecular basis for the dosing time-dependency of anti-allodynic effects of gabapentin in a mouse model of neuropathic pain
    Kusunose, N., Koyanagi, S., Hamanura, K., Matsunaga,N., Yoshida, M., Uchida, T., Tsuda, M., Inoue, K., Ohdo, S.
    MOLECULAR PAIN, 6, 83-90 (2010)
  • 141. Effect of physical properties of orally disintegrationg tablets on disintegration times as determined by a new apparatus
    Harada, T., Narazaki, R., Ohwaki, T. and Uchida, T.
    J. DRUG DEL. SCI. TECH., 20(5), 377-383 (2010)
  • 140. A new method for evaluating the bitterness of medicines in development using a taste sensor and a disintegration testing apparatus
    Harada, T., Uchida, T., Yoshida, M., Kobayashi, Y., Narazaki, R. and Ohwaki, T.
    Chem. Pharm. Bull., 58(8), 1009-1014 (2010)
  • 139. Neuroprotective effect of repeated Treatment with Hericium erinaceum in mice Subjected to middle cerebral Artery occlusion
    Hazekawa, M., Kataoka, A., Hayakawa, K., Uchimasu, T., Furuta, R., Irie, K., Akitake, Y., Yoshida, M., Fujioka, T., Egashira, N., Oishi, R., Mishima, K.,
    Mishima, K., Uchida, T., Iwasaki, K. and Fujiwara, M. J. Health Sci., 56(3), 296-303 (2010)
  • 138. Betterness suppression of the Kampo medicine ‘Orengedokuto’ using flavoured jellies
    Yoshida, M., Tokuyama, E., Hazekawa, M. and Uchida, T.
    Chem. Pharm. Bull., 58(4), 449-453 (2010)
  • 137. Prediction of incompatibility of ceftriaxone sodium with calcium ions using the ionic product
    Nakai, Y., Tokuyama, E., Yoshida, M. and Uchida. T.
    YAKUGAKU ZASSHI, 130(1), 95-102 (2010)
  • 136. Stability of gabexate mesilate products: Influence of the edition of maaitol
    Sakurai M, Abe H, Okamura N, Inoue Y, Akiyoshi T, Matsuyama K, Uchida T, Otsuka M.
    Biomed Mater Eng, 20(1), 13-20 (2010)
  • 135. 注射剤の配合変化によるリスクの回避−注射用セフトリアキソンナトリウムとカルシウム含有製剤の配合変化を例にして−
    中井由佳, 徳山絵生, 吉田都, 内田享弘
    静脈経腸栄養, 24(6), 1175-1182 (2009)
  • 134. 医薬品の苦味マスキング−味センサ法・官能試験法を用いた医薬品苦味評価系の構築−
    内田享弘
    粉体技術, 1(6), 39-44 (2009)
  • 133. 新しいアムロジン(R)OD錠(SUITAB-NEX(R)/アムロジピン口腔内崩壊錠)の服用性の定量評価
    内田享弘, 徳山絵生, 吉田都
    新薬と臨牀, 58(5), 854-862(2009)
  • 132. Optimization study for the dilution of phenytoin sodium injection: safe administration in clinical practice
    Y. Nakai, E. Tokuyama, K. Asahara, M. Yoshida, T. Uchida
    Asian J. Pharm. Sci., 4(6):324-330 (2009)
  • 131. Incompatibility of ceftriaxone sodium with calcium -containing Products
    Y. Nakai, E. Tokuyama, M. Yoshida, T. Uchida
    YAKUGAKU ZASSHI, 129(11), 1385-1392 (2009)
  • 130. Famotidine orally disintegrating tablets: bitterness comparison of original and generic products
    E. Tokuyama, C. Matsunaga, K. Yoshida, J.C. Mifsud, T. Irie, M. Yoshida, T. Uchida
    Chem. Pharm. Bull., 57(4),382-387 (2009)
  • 129. The effect of taste-odour interactions on the palatability of nutritional products for liver failure
    J. Mukai, E. Tokuyama, T. Ishizaka, S. Okada, T. Uchida.
    Asian J. Pharm. Sci., 4(1):46-55 (2009)
  • 128. Rapid infusion or dilution is effective in reducing phlebitis caused by epirubicin injection: experimental study in rabbits
    S. Anami, M. Nishikawa, K. Matsuyama, T. Kuwahara, Y. Murata, M. Yoshida, T. Uchida.
    Asian J. Pharm. Sci., 4(3):1-6 (2009)
  • 127. Effect of glutamine or alkaline ionized water on late diarrhea induced by irinotecan hydrochloride in Gunn rats
    S. Anami, K. Saegusa, M. Nishikawa, S. Matzno, T. Nakabayashi, H. Hagiwara, T. Uchida, K. Matsuyama.
    Asian J. Pharm. Sci., 4(2):96-105 (2009)
  • 126. Salting-out taste-masking system generates lag time with subsequent immediate release
    Yoshida T, Tasaki H, Maeda A, Katsuma M, Sako K, Uchida T.
    Int. J. Pharm., 365, 81-88 (2009)
  • 125. The effect of taste-odour interactions on the palatability of nutritional products for liver failure
    J. Mukai, E. Tokuyama, T. Ishizaka, S. Okada, T. Uchida
    Asian J. Pharm. Sci., 4(1), 46-55 (2009)
  • 124. Mechanism of controlled drug release from a salting-out taste-masking system
    Yoshida T, Tasaki H, Matsuda A, Katsuma M, Sako K, Uchida T.
    J. Control. Release, 131, 47-53 (2008)
  • 123. 経口苦味マスキング製剤の品質評価
    内田享弘、徳山絵生、吉田都、奥原有紀子
    月刊薬事, 57(11), 1701-1708 (2008)
  • 122. T. ISHIZAKA, S. OKADA, E. TOKUYAMA, J. MUKAI, T. UCHIDA
    Suppression of bitterness and improvement of palatability of commercial prednisolone powder
    Chem. Pharm. Bull., 56(10) 1395-1399 (2008)
  • 121. T. ISHIZAKA, S. OKADA, E. TOKUYAMA, J. MUKAI, T. UCHIDA
    Quality of twelve clarithromycin dry syrup formulations -bitterness, grittiness and uniformity of drug loading
    Chem. Pharm. Bull., 56(10) 1389-1394 (2008)
  • 120. 内田享弘
    ジェネリック医薬品の潮流
    日本臨牀, 66(8) 1615-1618 (2008)
  • 119. 内田享弘
    <総説>味センサを用いた苦味評価系の構築と製剤設計への応用
    薬剤学, 68(4) 220-229 (2008)
  • 118. 岡田幸恵、嶽本絵理、石坂敏彦、谷内加奈子、田上綾子、辻絵里子、内田享弘
    小児用抗菌薬の服用性に関する研究−懸濁・分散性および苦味強度の評価を中心にして−
    医療薬学, 34(1) 32-39 (2008)
  • 117. 嶽本絵理、岡田幸恵、向井淳治、石坂敏彦、内田享弘
    SD法による小児用抗菌薬の服用性評価
    医療薬学, 34(3) 263-267 (2008)
  • 116. 薬学教育6年制の早期体験学習の受け入れ施設へのアンケート調査とその解析
    長谷川豊、蓮池賢一、江崎圭吾、中尾尚子、平田千春、柴田香織、金啓二、西田英之、東和夫、平井みどり、徳山尚吾、福島昭二、山岡由美子、岩川精吾、松山賢治、内田享弘
    医療薬学, 34(1) 64-72 (2008)
  • 115. 薬学教育6年制の早期体験学習に関する学生へのアンケート調査とその解析
    平田千春、中尾尚子、柴田香織、山本朋子、沢崎高志、長谷川豊、蓮池賢一、西田英之、東和夫、金啓二、徳山尚吾、福島昭二、山岡由美子、岩川精吾、平井みどり、松山賢治、内田享弘
    医療薬学, 34(2) 204-213 (2008)
  • 114. M. Kataoka, E. Tokuyama, Y. Miyanaga, T. Uchida
    The taste sensory evaluation of medicinal plants and Chinese medicines
    Int. J. Pharm., 351 36-44 (2008)
  • 113. 岡田幸恵、嶽本絵理、石坂敏彦、内田享弘
    クラリスロマイシンドライシロップの先発品および後発品の品質評価
    医療薬学, 33(11) 905-912 (2007)
  • 112. J. Mukai, E. Tokuyama, T. Ishizaka, S. Okada, T. Uchida
    Inhibitory effect of aroma on the bitterness of branched-chain amino acid solutions
    Chem. Pharm. Bull., 55(11) 1581-1584 (2007)
  • 111. T. Akiyoshi, N. Tanaka, T. Nakamura, S. Matzno, K. Shinozuka, T. Uchida
    Effects of quinine on the intracellular calcium level and membrane potential of PC 12 cultures
    J. Pharm. Pharmacol., 59 1−6 (2007)
  • 110. T. Ishizaka, S. Okada, E. Takemoto, E. Tokuyama, E. Tsuji, J. Mukai, T. Uchida
    Enhanced bitterness intensity of macrolide dry syrup mixed with an acidic powder: methods of bitterness reduction
    Chem. Pharm. Bull., 55(10) 1452-1457 (2007)
  • 109. C. Matsunaga, S. Izumi, T. Furukubo, M. Satoh, T. Yamakawa, T. Uchida, D. Kadowaki, S. Hirata
    Effect of famotidine and lansoprazole on serum phosphorus levels in hemodialysis patients on calcium carbonate therapy
    Clinical Nephrology, 68(2) 93-98 (2007)
  • 108. 熊谷智香、徳山絵生、石坂敏彦、向井淳治、浅香清一、内田享弘
    抗菌剤の内服コンプライアンス向上を目指して−味覚センサによる苦味予測とその活用−
    医療薬学, 33(8) 659-665 (2007)
  • 107. Y. Hashimoto, C. Matsunaga, E. Tokuyama, E. Tsuji, T. Uchida, H. Okada
    The Quantitative Prediction of Bitterness-Suppressing Effect of Sweeteners on the Bitterness of Famotidine by Sweetness-Responsive Sensor
    Chem. Pharm. Bull., 55(5) 739-746 (2007)
  • 106. 千原里美、徳山絵生、上田宏、大澤万智子、豊原朋子、内田享弘
    携帯型持続注入ポンプの特性と薬学的安全管理
    医薬ジャーナル, 43(3) 919-923
  • 105. 内田享弘
    ジェネリック薬の有用性と課題
    西宮市医師会医学雑誌, 12 15-18 (2007)
  • 104. 内田享弘、徳山絵生
    医薬品開発における味覚センサの利用
    表面,44,1-16(2006)
  • 103. E. Tokuyama, T. Shibasaki, H. Kawabe, J. Mukai, S. Okada and T. Uchida
    Bitterness Suppression of BCAA Solutions by L-ornithine
    Chem. Pharm. Bull., 54(9) 1288-1292 (2006)
  • 102. 中井由佳、徳山絵生、辻絵里子、内田享弘
    注射用パニペネム製剤の安定性(注射剤に関する研究 第1報)
    医療薬学, 32(5) 429-435 (2006)
  • 101. 向井淳治、石坂敏彦、徳山絵生、辻絵里子、内田享弘
    半消化態経腸栄養剤の服用感の評価
    医療薬学, 32(5) 383-391 (2006)
  • 100. Y. Hashimoto, E. Tsuji, Y. Miyanaga, T. Uchida, H. Okada
    The use of the artificial taste sensor in the evaluation of taste masking and sustained-release characteristics of trimebutine formulations.
    J. Drug Del. Sci. Tech., 16(3) 235-240 (2006)
  • 99. E. Tsuji, T. Uchida, A. Fukui, R. Fujii, H. Sunada
    Evaluation of Bitterness Suppression of Macrolide Dry Syrups by Jellies
    Chem. Pham. Bull., 54(3) 310-314 (2006)
  • 98. 石坂敏彦、辻絵里子、向井淳治、浅香清一、内田享弘
    錠剤の分割・粉砕化による苦味増強の評価(医薬品の服用性に関する研究 第24報)
    医療薬学, 32(3) 259-265 (2006)
  • 97.向井淳治、石坂敏彦、浅香清一、山絵生、辻絵里子、内田享弘
    経腸栄養剤の味評価(医薬品の服用性に関する研究 第23報)
    医療薬学, 32(1) 13-20 (2006)
  • 96. Yoshida, M., Yasuda, N., Nishikata, M., Okamoto, K., Uchida, T., Matsuyama, K.
    New recommendations for vancomycin dosage for patiens with MRSA pneumonia with various degrees of renal function impairment
    J. Infect. Chemother., 11, 182-188 (2005)
  • 95. 立木秀尚、内山仁、奥田豊、内田涼子、小林義和、内田享弘
    味覚センサを用いたファモチジン口腔内崩壊錠の苦味評価
    医学と薬学54, 321-327 (2005)
  • 94. M. Kataoka, K. Yoshida, Y. Miyanaga, E. Tsuji, E. Tokuyama, T. Uchida
    Evaluation of the taste and smell of bottled nutritive drinks
    Int. J. Pharm., 305, 13-21 (2005)
  • 93. 辻 絵里子、高田美幸、内田享弘 味覚センサを用いたマクロライド系ドライシロップの苦味評価(苦味マスキングに関する報告 第22報)
    医療薬学, 31(3), 186-193(2005)
  • 92. 内田享弘
    オルニチンの苦味マスキング効果
    Bioindustry, 11, 76-84 (2004)
  • 91. T. Ogawa, K. Hoshina, J. Haginaka, C. Honda, T. Tanimoto and T. Uchida
    Screening of bitterness-suppressing agents for quinine : The use of molecularly imprinted polymers
    Journal of Pharmaceutical Sciences., 94(2), 353-362 (2005)
  • 90. 辻 絵里子、内田享弘
    味覚センサによるアジスロマイシン水和物(ジスロマック細粒小児用)の苦味評価
    医薬ジャーナル, 46(12), 3317-3325 (2004)
  • 89. 内田享弘
    苦味を抑制するアミノ酸の発見!
    食の科学 No.317, 56-64 (2004)
  • 88. 小笹維也、秋田恵子、飛松佳江、山崎淳治、山本佐代子、堺純一、林田知大、内田享弘
    ニフェランタン(R)CR錠20・同40(膨潤溶解型ニフェジピン徐放錠)の製剤特性
    医療と薬学, 52(7), 101-105 (2004)
  • 87. M. Kataoka, Y. Miyanaga, E. Tsuji, T. Uchida.
    Evaluation of bottled nutritive drinks using a taste sensor
    Int. J. Pharm., 279(7), 107-114 (2004)
  • 86. T. ISHIZAKA, Y. MIYANAGA, J. MUKAI, K. ASAKA, Y. NAKAI, E. TSUJI, and T. UCHIDA
    Bitterness Evaluation of Medicines for Pediatric Use by a Taste Sensor
    Chem. Pharm. Bull., 52(8), 943-948 (2004)
  • 85. J. MUKAI, Y. MIYANAGA, T. ISHIZAKA , K. ASAKA ,Y. NAKAI, E. TSUJI, and T. UCHIDA
    Quantitative taste evaluation of total enteral nutritions
    Chem. Pharm. Bull., 52(12), 1416-1421 (2004)
  • 84. Y. Miyanaga, J. Mukai, T. Mukai, M. Odomi, T. Uchida
    Suppression of the Bitterness of Enteral Nutrients Using Increased Particle Sizes of Branched-Chain Amino Acids (BCAAs) and Various Flavours: a Taste Sensor Study
    Chem. Pharm. Bull., 52(4), 490-493 (2004)
  • 83. T. Ogawa, T. Nakamura, E. Tsuji, Y. Miyanaga, H. Nakagawa, H. Hirabayashi, and T. Uchida
    The Combination Effect of L-Arginine and NaCl on Bitterness Suppression of Amino Acid Solutions
    Chem. Pharm. Bull., 52(2), 172-177 (2004)
  • 82. Miyanaga,Y., Inoue,N., Ohnishi,A., Fujisawa,E., Yamaguchi,M. and Uchida,T.
    Quantitative Prediction of the Bitterness Suppression of Elemental Diets by Various Flavours Using a Taste Sensor
    Pharm. Res., 20(12), 1932-1938 (2003)
  • 81. Uchida,T., Tanigake,A., Miyanaga,Y., Matsuyama,K., Kunitomo,M., Kobayashi,K., Ikezaki,H. and Taniguchi,A.
    Evaluation of the bitterness of antibiotics using a taste sensor
    J. Pharm. Pharmacol., 55(11), 1479-1485, (2003)
  • 80. T. Nakamura, T. Akiyoshi, N. Tanaka, K. Shinozuka, S. Matzno, T. Nakabayashi, K. Matsuyama, M. Kashiwayanagi and T. Uchida
    Effect of Quinine Solutions on Intracellular Ca2+ Levels in Neuro-2a Cells-Conventional Physiological Method for the Evaluation of Bitterness-
    Biol. Pharm. Bull., 26(11), 1637-1640 (2003)
  • 79. A. Tanigake, Y. Miyanaga, T. Nakamura, E. Tsuji, K. Matsuyama, M. Kunitomo and T. Uchida
    The Bitterness Intensity of Clarithromycin Evaluated by a Taste Sensor
    Chem. Pharm. Bull., 51(11), 1241-1245 (2003)
  • 78. 村山(田鶴谷)恵子, 松野純男, 山田和子, 中林利克, 内田享弘, 松山賢治, 三嶋基弘
    サプリメントとしてのビタミンとHMG-CoA還元酵素阻害剤による横紋筋融解症発症のリスク
    日本食品化学学会誌, 10(2), 78-84 (2003)
  • 77. 内田享弘, 宮永陽子
    味センサを用いた薬物の苦味評価(下)
    月刊薬事, 45(9), 1741-1748 (2003)
  • 76. 内田享弘
    味センサを用いた薬物の苦味評価(上)
    月刊薬事, 45(8), 1477-1483 (2003)
  • 75. 内田享弘
    味センサによる薬物の苦味・苦味マスキング効果の定量化
    粉体と工業, 35(7), 32-40 (2003)
  • 74. S. Matzno, K. Tazuya-Murayama, H. Tanaka, S. Yasuda, M. Mishima, T. Uchida, T. Nakabayashi and K. Matsuyama
    Evaluation of the synergistic adverse effects of concomitant therapy with statins and fibrates on rhabdomyolysis
    J. Pharm. Pharmacol., 55(6), 795-802 (2003)
  • 73. Y. Miyanaga, Y. Kobayashi, H. Ikezaki, A. Taniguchi and T. Uchida
    Bitterness Prediction or Bitterness Suppression in Human Medicines Using a Taste Sensor
    Sensor & Materials., 14, 455-465 (2002)
  • 72. Y.Miyanaga, A.Tanigake, T.Nakamura, Y.Kobayashi, H.Ikezaki, A.Taniguchi, K.Matsuyama and T.Uchida
    Prediction of the Bitterness of Single, Binary- and Multiple-Component Amino Acid Solutions Using a Taste Sensor.
    Int. J. Pharm., 248, 207-218 (2002)
  • 71. T. Nakamura, A. Tanigake, Y. Miyanaga, T. Ogawa, T. Akiyoshi, K. Matsuyama and T. Uchida
    The effect of various substances on the bitterness suppression of quinine - Human gustatory sensation, binding and sensory study ?
    Chem. Pharm. Bull., 50, 1589-1593 (2002)
  • 70. Y. Hashimoto, M. Tanaka, H. Kishimoto, H. Shiozawa, K. Hasegawa, K. Matsuyama and T. Uchida
    Preparation, characterization and taste-masking properties of polyvinylacetal diethylaminoacetate microspheres containing trimebutine.
    J.Pharm.Pharmacol., 54,1323-1328 (2002)
  • 69. 小川多津子, 石田規子, 問田有香, 内田享弘, 松山賢治
    後発医薬品への病院薬剤師の取り組み
    日本病院薬剤師会雑誌, 38(5), 47-50 (2002)
  • 68. K. Matsuyama, K. Nakagawa, A. Nakai, Y. Konishi, M. Nishikata, H. Tanaka, T. Uchida
    Evaluation of Myopathy Risk for HMG-CoA Reductase Inhibitors by Urethane Infusion Method.
    Biol. Pharm. Bull., 25(3), 346-350 (2002)
  • 67. 西山祐美, 北田徳昭, 関戸聡子, 小林睦, 渡雅克, 内田享弘, 松山賢治, 黒田和夫
    4週間卒前実務実習カリキュラムの現状と課題 −本院での実習を例として−
    病院薬学, 26(2), 184-191 (2002)
  • 66. T. Uchida, N. Yasuda and K. Matsuyama
    Preparation and Characterization of Biodegradable or Enteric-coated Microspheres Containing the Protease Inhibitor Camostat.
    J. Pharm. Pharmacol., 53(2), 255-261 (2001)
  • 65. T. Uchida, Y. Kobayashi, Y. Miyanaga, R. Toukubo, H. Ikezaki, A. Taniguchi and K. Matsuyama
    A New Method to Evaluate the Bitterness of Medicines by Semi-continuous Measurement of Adsorption using a Taste Sensor.
    Chem. Pharm. Bull., 49(10), 1336-1339 (2001)
  • 64. T. Uchida,Y. Toida,S. Sakakibara,Y. Miyanaga,M. Nishikata, K. Tazuya, N. Yasuda and K. Matsuyama
    Preparation and Characterization of Insulin-Loaded Acrylic Hydrogels containing Absorption Enhancers.
    Chem. Pharm. Bull., 49(10), 1261-1266 (2001)
  • 63. T. Uchida, Y. Miyanaga, H. Tanaka, K. Wada, S. Kurosaki, T. Ohki, M. Yoshida and K. Matsuyama
    Quantitative evaluation of the bitterness of commercial medicines using a taste sensor.
    Chem. Pharm. Bull., 48(11), 1843‐1845 (2000)
  • 62. T. Uchida, Y. Toida, Y. Miyanaga, K. Machida, K. Wada, T. Ohki and K. Matsuyama
    Preparation and Characterization of acrylic hydrogel neutralized by basic amino acids.
    Chem. Pharm. Bull., 48(11), 1828-1830 (2000)
  • 61. 小川多津子, 大澤直, 内田享弘, 松山賢治
    後発医薬品評価における病院薬剤師と薬科大学の連携−ロキソプロフェンナトリウム錠の溶出試験を例にして−
    Jpn. J. Hosp. Pharm., 26(4), 427-431 (2000)
  • 60. J. Uchida, T.Sekiya, N.Toida, Y. Yasuda, N. Tazuya, K. Nishikata, M. Matsuyama
    Zero-order Release from Cylindrical Xerogel Preparation.
    Chem. Pharm. Bull., 47(10), 1655-1658 (1999)
  • 59. T. Uchida, S. Sakakibara, Y. Toida, N. Nagareya, N. Yasuda and K. Matsuyama
    Rectal Insulin Delivery Using Bioadhesive Hydrogel Preparation Containing Lauric Acid as an Enhancer.
    Pharmacy and Pharmacology Communications, 5(5), 523-527 (1999)
  • 58. H. Matsuo, M. Ryu, A. Nagata, T. Uchida, J. Kawakami, K. Yamamoto, T. Iga and Y. Sawada
    Neurotoxicodynamics of the interaction between ciprofloxacin and foscarnetin mice.
    Antimicrob. Agents Chemother., 42, 691-694 (1998)
  • 57. T. Uchida, K. Shiosaki, Y. Nakada, K. Fukuda, Y. Eda, N. Nagareya and K. Matsuyama
    Microencapsulation of hepatitis B core antigen for vaccine preparation.
    Pharmaceutical Research, 15, 1708-1713 (1998)
  • 56. N. Nagareya, T. Uchida and K. Matsuyama
    Preparation and characterization of enteric microspheres containing bovine insulin by a w/o/w emulsion solvent evaporation method.
    Chem. Pharm. Bull., 46, 1613-1617 (1998)
  • 55. T. Uchida, N. Nagareya, S. Sakakibara, Y. Konishi, S. Nakai, M. Nishikata, K. Matsuyama and K. Yoshida
    Preparation and Characterization of Polylactic Acid Microspheres Containing Bovine Insulin by a w/o/w Emulsion Solvent Evaporation Method.
    Chem. Pharm. Bull., 45, 1539-1543 (1997)
  • 54. T. Uchida, T. Yasutake, M. Nishikata, A. Nakai, Y. Konishi, N. Nagareya, K. Matsuyama
    In-vitro Zero-order Release of Anti-inflammatory Drugs From Pullulan Acetate Phthalate Microspheres.
    Pharmaceutical Sciences, 3(4), 387-390 (1997)
  • 53. T. Uchida, K. Yoshida, Y. Nakada, N. Nagareya, Y. Konishi, A. Nakai, M. Nishikata and K. Matsuyama
    Preparation and Characterization of Polylactic Acid Microspheres Containing Water-Soluble Anesthetics with Small Molecular Weight.
    Chem. Pharm. Bull., 45(3), 513-517 (1997)
  • 52. Y. Uchida, K. Yamabe, M. Nishikata, A. Nakai, N. Nagareya, Y. Konishi and K. Matsuyama
    Gastrointestinal Absorption of Chlorothiazide Enhanced by Commercial Swelling Polymers in Dog.
    Pharmaceutical Sciences, 3(2), 183-187 (1997)
  • 51. A.Nakai, M. Nishikata, T. Uchida, M. Ichikawa and K. Matsuyama
    Effect of Cholestyramine on the Pharmacokinetics and Pharmacodynamics of Bezafibrate in Rats.
    Jpn. J. Hosp. Pharm., 23(2), 121-126 (1997)
  • 50. A.Nakai, M. Nishikata, T. Uchida, M. Ichikawa and K. Matsuyama
    Enhanced Myopathy Following Administration of Hypolipidemic Agents Under Urethane Anesthesia Bilo. Pharm. Bull., 20(1), 104-106 (1997)
  • 49. N. Sawada, T. Uchida, H. Matsuo, H. Takanaga and Y. Sawada
    Effect of Triazole Antifungal Agents on the Drug Secretion Process in Rat Small Intestine.
    Pharm. Sci., 2(12), 505-507 (1996)
  • 48. T. Uchida, A. Yagi, Y. Oda and S. Goto
    Microencapsulation of ovalbumin in poly(lactide-co-glycolide)by an oil in oil solvent evaporation method.
    J. Microencapsulation, 13(5), 509-518 (1996)
  • 47. T. Uchida , K. Yoshida and S. Goto
    Preparation and characterization of polylactic acid microspheres containing water-soluble dyes using a novel W/O/W emulsion solvent evaporation method.
    J. Microencapsulation, 13(3), 219-228 (1996)
  • 46. T. Uchida, A. Yagi, Y. Oda, Y. Nakada and S. Goto
    Instability of bovine insulin in poly(lactide-co-glycolide)(PLGA) microspheres.
    Chem. Pharm. Bull., 44(1), 235-236 (1996)
  • 45. C. K. Lee, K. Kitagawa, T. Uchida, N. S. Kim, and S. Goto
    Transdermal Delivery of Theophylline Using Ethanol/Panasate800 - Ethylcellulose Gel Preparation.
    Biol. Pharm. Bull., 18, 176-180 (1995)
  • 44. T. Uchida, S. Goto, and T. P. Foster
    Particle Size Studies for Subcutaneous Delivery of Poly(lactide-co-glycolide) Microspheres containing Ovalbumin as Vaccine Formulation.
    J. Pharm. Pharmacol., 46, 1214-1221 (1995)
  • 43. T. Uchida, K. Yoshida, and A. Ninomiya, and S. Goto
    Optimization of preparative conditions for polylactide (PLA) microspheres containing ovalbumin.
    Chem. Pharm. Bull., 43(9), 1569-1573 (1995)
  • 42. T. Uchida, S. Goto, and T. P. Foster
    Particle Size Studies for Subcutaneous Delivery of Poly(lactide-co-glycolide) Microspheres containing Ovalbumin as Vaccine Formulation.
    J. Pharm. Pharmacol., 47(7), 556-560 (1995)
  • 41. H. Umejima, A. Kikuchi, N.-S. Kim, T. Uchida, and S. Goto
    Preparation and evaluation of eudragit gels [:rectal absorption of 5-Fluorouracil from eudispert hv gels in rats.
    J. Pharm. Sci., 84(2), 199-202 (1995)
  • 40. C.- K. Lee, K. Kitagawa, T. Uchida, N.-S. Kim, and S. Goto
    Transdermal Delivery of Theophylline Using Ethanol/Panasate800 - Ethylcellulose Gel Preparation.
    Bilo. Pharm. Bull., 18(1), 176-180 (1995)
  • 39. C.- K. Lee, T. Uchida, K. Kitagawa, A. Yagi, N.-S. Kim, and S. Goto
    Relationship between lipophilicity and skin permeability of various drugs from an ethanol/water/lauric acid system.
    Bilo. Pharm. Bull., 17(10), 1421-1424 (1994)
  • 38. 梅島啓之, 原田貴弘, 金洛瑞, 内田享弘, 後藤茂
    直腸薬物送達を指向した新規潰瘍性大腸炎治療薬ONO-4057の生体粘膜不着性Eudispertゲル製剤
    Drug Delivery System, 9(9), 363-369 (1994)
  • 37. T. Uchida and S. Goto
    Oral delivery of poly(lactide-co-glycolide)microspheres containing ovalbumin as vaccine formulation: particle size study.
    Bilo. Pharm. Bull., 17(9), 1272-1276 (1994)
  • 36. T. Uchida, S. Martin, T. P. Foster, R. C. Wardley, S. Grimm
    Dose and load studies for subcutaneous and oral delivery of poly(lactide-co-glycolide) microspheres containing ovalbumin.
    Pharm. Res., 11(7), 1009-1015 (1994)
  • 35. C.- K. Lee, T. Uchida, K. Kitagawa, A. Yagi, N.-S. Kim, and S. Goto
    Skin permeability of various drugs with different lipophilicity.
    J. Pharm. Sci., 83(4), 562-565 (1994)
  • 34. 後藤茂, 李千九, 八木明, 内田享弘, 金洛瑞
    Lauric Acid添加Ethanol/Water-Hydroxypropylmethyl-celluloseゲル製剤からのTheophyllineの経皮吸収性
    Drug Delivery System, 9(11), 423-430 (1994)
  • 33. A.Noda, Y. Ono, K. Inokuchi, H. Noda, T. Uchida
    Detection of 1-acetoamino-3-(1-maphtyloxy)-2-propanol as a new metabolite of propranolol.
    Bilo. Pharm. Bull., 17(10), 1433-1435 (1994)
  • 32. C. K. Lee, T. Uchida, E. Noguchi, N. S. Kim, and S. Goto
    Skin Permeation Enhancement of Tegafur by Ethanol/Panasate 800 or Ethanol/Water Binary Vehicle and Combined Effect of Fatty Acids and Fatty Alcohols.
    J. Pharm. Sci., 82, 1155-1159 (1993)
  • 31. S. Goto, T. Uchida, C. K. Lee, T. Yasutake, and J. B. Zhang
    Effect of Various Vehicles on Ketoprofen Permeation across Excised Hairless Mouse Skin.
    J. Pharm.Sci., 82, 959-963 (1993)
  • 30. C.- K. Lee, T. Uchida, K. Kitagawa, A. Yagi, N.-S. Kim, and S. Goto
    Effect of hydrophilic vehicles on skin permeation of tegafur, alclofenac and ibuprofen with or without permeation enhancers
    Bilo. Pharm. Bull., 16(12), 1264-1269 (1993)
  • 29. C.- K. Lee, T. Uchida, E. Noguchi, N.-S. Kim, and S. Goto
    Skin pemeation enhancement of tegafur by ethanol/panasate 800 of ethanol/water binary vehicle and combined effect of fatty acids and fatty alcohols
    J. Pharm. Sci., 82(11), 1155-1159 (1993)
  • 28. S. Goto, T. Uchida, C.- K. Lee, T. Yasutake, and J.-B. Zhang
    Effect of various vehicles on ketoprofen permeation across excised hairless mouse skin
    J.Pharm.Sci., 82(9), 959-963 (1993)
  • 27. T. Miyakawa, W. Zhang, T. Uchida, N.-S. Kim, and S. Goto
    In vivo release of water-soluble drugs from stabilized water-in-oil-in-water (W/O/W)type multiple emulsions following intravenous administrations using rats
    Bilo. Pharm. Bull., 16(2), 268-272 (1993)
  • 26. H. Umejima, N.-S. Kim, T. Ito, M. Kawata, T. Uchida, and S. Goto
    Preparation and evaluation of eudragit gels. Y:In vivo evaluation of eudispert rectal hydrogel and xerogel containing salicylamide
    J. Pharm. Sci., 82(2), 195-199 (1993)
  • 25. 李千九, 内田享弘, 北川和久, 金洛瑞
    Ethanol/panasate 800混合系及びethanol/water混合系を用いたsteroid類薬物の皮膚透過性
    Drug Delivery System, 8(2), 283-289 (1993)
  • 24. 李千九, 内田享弘, 北川和久, 金洛瑞, 後藤茂
    Ethanol/panasate 800混合系によるalcofenacの経皮吸収促進効果
    Drug Delivery System, 8(2), 121-129 (1993)
  • 23. T. Uchida, C.- K. Lee, N. Sekiya and S. Goto
    Enhancement effect of an ethanol/panasate 800 binary vehicle on anti-inflammatory drug permeation across excised hairless mouse skin
    Bilo. Pharm. Bull., 16(2), 168-171 (1993)
  • 22. 山辺 和, 宮川辰治, 内田享弘, 金 洛瑞, 後藤 茂
    Eudragit RS を用いたケトプロフェン含有マイクロカプセルの調製と坐剤への適用.
    薬剤学, 52, 51-58 (1992)
  • 21. T. Uchida, T. Yasutake, and S. Goto
    Utility of Mixture of Commercially Available Polymers as Constituents of Sustained-release Microcapsules Containing Cefadroxil or Theophylline.
    Chem. Pharm. Bull., 40, 463-466 (1992)
  • 20. 梅島啓之, 金洛瑞, 足達敬子, 内田享弘, 後藤茂
    サリチルアミド包含レクタルゲル製剤の中空坐剤への応用
    薬剤学, 52(12), (1992)
  • 19. N.-S. Kim, H. Umejima, T. Ito, T. Uchida, and S. Goto
    Preparation and evaluation of eudragit Gels X:rectal gel preparations for sustained-release and avoidance from first-pass metabolism of lidocaine
    Chem. Pharm. Bull., 40(12), 2800-2804 (1992)
  • 18. N.-S. Kim, T. Ito, M. Kawata, T. Uchida, and S. Goto
    Preparation and evaluation of Eudragit Gels W:rectal gel preparations for sustained-release of avoidance from first-pass metabolism of propentofylline
    J.Pharm.Sci., 81, 904-907 (1992)
  • 17. N.-S. Kim, M. Kawata, T. Uchida, and S. Goto
    Preparation and evaluation of Eudragit Gels V:rectal gel preparations for sustained release of pentoxifylline
    J. Pharm. Sci., 81(6), 537-540 (1992)
  • 16. 山辺和, 宮川辰治, 内田享弘, 金洛瑞, 後藤茂
    Eudragit RSを用いたケトプロフェン含有マイクロカプセルの調製と坐剤への適用
    薬剤学, 52(1) 51-58 (1992)
  • 15. 宮川辰治, 内田享弘, 関屋昇, 金洛瑞, 後藤茂
    5-aminosalicylic acid含有マイクロカプセル分散坐剤による大腸粘膜指向性の試み
    Drug Delivery System, 7(1), 57-62 (1992)
  • 14. T. Uchida, T. Yasutake, and S. Goto
    Utility of mixture of commercially available polymers as constituents of sustained-release microcapsules containing cefadroxil or theophylline
    Chem. Pharm. Bull., 40(1), 463-466 (1992)
  • 13. 張薇, 宮川辰治, 内田享弘, 後藤茂
    水溶性薬物を包含したW/O/W型複合エマルションの調製とその薬物放出性のin vitro評価(エマルション製剤の調製と評価 第2報)
    薬学雑誌, 51(1), 73-80 (1992)
  • 12. 後藤茂, 中田克己, 宮川辰治, 張薇, 内田享弘
    W/O/W型複合エマルションの内水相中に封入された水溶性薬物の放出性(エマルション製剤の調製と評価 第1報)
    薬学雑誌, 50(6), 702-708 (1991)
  • 11. 内田享弘, 中村永人, 安武拓治, 後藤 茂
    ビ−グル犬による薬物包含プルランアセテ−トフタレ−トマイクロカプセルのin vivo評価.
    薬剤学, 50, 369-375 (1990)
  • 10. 内田享弘, 中村永人, 安武拓治, 藤本一郎, 後藤 茂, 青山敏信
    薬物包含プルランアセテ−トフタレ−トマイクロカプセルの調製と溶出試験.
    薬剤学, 50, 360-368 (1990)
  • 9. 内田享弘、藤本一郎、後藤 茂
    ビ−グル犬による経口用セフェム系抗生物質包含アセチル化プルランマイクロカプセルの薬物速度論的評価.
    薬剤学, 49, 53-58 (1989)
  • 8. 内田享弘, 藤本一郎, 後藤 茂
    経口用セフェム系抗生物質包含アセチル化プルランマイクロカプセルの調製と溶出試験.
    薬剤学, 49, 46-52 (1989)
  • 7. T. Uchida, I. Fujimoto, and S. Goto
    Biopharmaceutical Evaluation of Sustained-release Ethyl Cellulose Microcapsules Containing Amoxicillin Using Beagle Dogs.
    Chem. Pharm. Bull., 37, 3416-3419 (1989)
  • 6. T. Tsujiyama, N. Suzuki, M. Kawata, T. Uchida, and S. Goto
    Preparation and Pharmacokinetic and Pharmacodynamic Evaluation of Hydroxy Propyl Cellulose-Ethyl Cellulose Microcapsules Containing Piretanide.
    J. Pharmacobio.-Dyn., 12, 311-323 (1989)
  • 5. T. Uchida, and S. Goto
    Biopharmaceutical Evaluation of Sustained-release Ethyl Cellulose Microcapsules Containing Cefadroxil and Cephradine Using Beagle Dogs.
    Chem. Pharm. Bull., 36, 2135-2144 (1988)
  • 4. 内田享弘, 藤本一郎, 後藤 茂, 青山敏信
    セフラジンまたはセファドロキシルを包含したエチルセルロースマイクロカプセルの調製と評価
    薬剤学, 47, 254-259 (1987)
  • 3. T. Tsujiyama, N. Suzuki, T. Uchida, M. Kawata, and S. Goto
    Comparison between Rabbits and Beagle Dogs of Sustained Release Effect of Gelatin Microcapsules Containing Piretanide.
    J. Controlled Release, 5, 103-112 (1987)
  • 2. T. Uchida, M. Kawata, and S. Goto
    In vivo Evaluation of Ethyl Cellulose Microcapsules Containing Ampicillin Using Rabbits, Beagle Dogs and Humans.
    J. Pharmacobio-Dyn., 9, 631-637 (1986)
  • 1. S. Goto, T. Uchida, and T. Aoyama
    Preparation and Biopharmaceutical Evaluation of Microcapsules of Ampicillin.
    J. Pharmacobio-Dyn., 8, 270-277 (1985)

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