研究業績
94) Kazuyuki Furuta, Takehiro Yoshioka, Kana Nishikaze, Noriko Yoshikawa, Kazuki Nakamura and Chikara Kaito
" Nicotine- and tar-removed cigarette smoke extract modulates the antigen presentation function of mouse bone marrow-derived dendritic cells, "
Microbiology and Immunology, 67 (5): 264-273 (2023)
93) Midori Matsushita, Kumi Futawaka, Misa Hayashi, Kana Murakami, Mana Matsutani, Mayuko Hatai, Yukiko Watamoto, Noriko Yoshikawa, Kazuki Nakamura, Tetsuya Tagami and Kenji Moriyama
"Cigarette smoke extract modulates functions of peroxisome proliferator-activated receptors"
Biol Pharm Bull, 42 (10): 1628-1636 (2019)
92) Mayuko Hatai, Shizuyo Horiyama, Noriko Yoshikawa, Eriko Kinoshita, Satomi Kagota, Kazumasa Shinozuka and Kazuki Nakamura
"Trans-2-pentenal, an active compound in cigarette smoke, identified via its ability to form adducts with glutathione"
Chem Pharm Bull, 67 (9): 1000-1005 (2019)
91) Seiichi Takeda, Takao Toda and Kazuki Nakamura
"Effects of medium molecular weight heparinyl phenylalanine on type I hypersensitivity"
In Vivo, 33 (1): 53-55 (2019)
90) Shizuyo Horiyama, Mayuko Hatai, Atsushi Ichikawa, Noriko Yoshikawa, Kazuki Nakamura and Masaru Kunitomo
"Detoxification mechanism of α,β-unsaturated carbonyl compounds in cigarette smoke observed in sheep erythrocytes"
Chem Pharm Bull, 66 (7): 721-726 (2018)
89) Seiichi Takeda, Takao Toda and Kazuki Nakamura
"Effects of medium molecular weight heparinyl arginine on scorpion venom-induced pulmonary edema in rats"
In Vivo, 32 (3): 537-539 (2018)
88) Mayuko Hatai, Noriko Yoshikawa, Eriko Kinoshita, Shizuyo Horiyama, Satomi Kagota, Kazumasa Shinozuka and Kazuki Nakamura
"Invasion-inhibiting effects of gaseous components in cigarette smoke on mouse rectal carcinoma colon-26 cells"
In Vivo, 32 (3): 493-497 (2018)
87) Misa Hayashi, Kumi Futawaka, Midori Matsushita, Mayuko Hatai, Noriko Yoshikawa, Kazuki Nakamura, Tetsuya Tagami and Kenji Moriyama
"Cigarette smoke extract disrupts transcriptional activities mediated by thyroid hormones and its receptors"
Biol Pharm Bull, 41 (3): 383-393 (2018)
86) Kana Maruyama, Satomi Kagota, John McGuire, Hirokazu Wakuda, Noriko Yoshikawa, Kazuki Nakamura and Kazumasa Shinozuka
"Age-related changes to vascular protease-activated receptor 2 in metabolic syndrome: A relationship between oxidative stress, receptor expression and endothelium-dependent vasodilation"
Can J Physio Pharmacol, 95 (4): 356-364 (2017)
85) Seiichi Takeda, Takao Toda and Kazuki Nakamura
"Effects of Medium Molecular Weight Heparinyl Phenylalnine on Superoxide Dismutase Activity in Mice"
In Vivo, 30 (6): 841-844 (2016)
84) Seiichi Takeda, Takao Toda and Kazuki Nakamura
"Inhibitory Effects of Medium Molecular Weight Heparinyl Amino Acid Derivatives on Ischemic Paw Edema in Mice"
In Vivo, 30 (4): 433-437 (2016)
83) Shizuyo Horiyama, Masaru Kunitomo, Noriko Yoshikawa and Kazuki Nakamura
"Mass Spectrometric Approaches to the Identification of Potential Ingredients in Cigarette Smoke Causing Cytotoxicity"
Biol Pharm Bull, 39 (6): 903-908 (2016)
82) Kazuki Nakamura
"Recent Advances in Research on Bioactive Ingredients in Cigarette Smoke:Foreword"
Biol Pharm Bull, 39 (6): 897 (2016)
81) Shizuyo Horiyama, Mayuko Hatai, Yuta Takahashi, Sachiko Date, Tsutomu Masujima, Chie Honda, Atsushi Ichikawa, Noriko Yoshikawa, Kazuki Nakamura, Masaru Kunitomo and Mitsuo Takayama
"Intracellular Metabolism of α,β-Unsaturated Carbonyl Compounds, Acrolein, Crotonaldehyde and Methyl Vinyl Ketone, Active Toxicants in Cigarette Smoke: Participation of Glutathione Conjugation Ability and Aldehyde-Ketone Sensitive Reductase Activity"
Chem Pharm Bull, 64 (6): 585-593 (2016)
80) Seiichi Takeda, Takao Toda and Kazuki Nakamura
"Middle molecular weight heparinyl amino acid derivatives (MHADs) function as indirect radical scavengers in vitro "
Pharmacology and Pharmacy, 7 (3): 117-123 (2016)
79) Kana Maruyama, Satomi Kagota, John J. McGuire, Hirokazu Wakuda, Noriko Yoshikawa, Kazuki Nakamura and Kazumasa Shinozuka
"Enhanced nitric oxide synthase activation via protease-activated receptor 2 is involved in the preserved vasodilation in aortas from metabolic syndrome rats "
J Vasc Res, 52 (4): 232-243 (2016)
78) Narayanan K. Narayanan, Kazuhiro Kunimasa, Yukio Yamori, Mari Mori, Hideki Mori, Kazuki Nakamura , George Miller, Upender Manne, Amit K. Tiwari and Bhagavathi Narayanan
"Antitumor activity of melinjo (Gnetum gnemon L.) seed extract in human and murine tumor models in vitro and in a colon-26 tumor-bearing mouse model in vivo"
Cancer Med, 4 (11): 1767-1780 (2015)
77)Hirokazu Wakuda, Shino Miyauchi, Kana Maruyama, Satomi Kagota, Kazuki Nakamura, Keizo Umegaki, Shizuo Yamada and Kazumasa Shinozuka
"Differential effects of mitogen-activated protein kinase pathway inhibitors on P-glycoprotein activation"
ADMET & DMPK, 3 (1): 77-83 (2015)
76)Chiharu Tabata, Rie Tabata, Yuta Takahashi, Kazuki Nakamura and Takashi Nakano
"Thalidomide prevents cigarette smoke extract-induced lung damage"
Int Immunopharmacol, 25 (2): 511-517 (2015)
75) Kazuki Nakamura, Kazumasa Shinozuka and Noriko Yoshikawa
"Anticancer and antimetastatic effects of cordycepin, an active component of Cordyceps sinensis"
J Pharmacol Sci, 127 (1): 53-56 (2015)
74)Satomi Kagota, Kana Maruyama, Hirokazu Wakuda, John J. McGuire, Noriko Yoshikawa, Kazuki Nakamura and Kazumasa Shinozuka
"Disturbance of vasodilation via protease-activated receptor 2 in SHRSP.Z-Lepr(fa)/IzmDmcr rats with metabolic syndrome"
Vascul Pharmacol, 63 (1): 46-54 (2014)
73) Shizuyo Horiyama, Yuta Takahashi, Mayuko Hatai, Chie Honda, Kiyoko Suwa, Atsushi Ichikawa, Noriko Yoshikawa, Kazuki Nakamura, Masaru Kunitomo, Sachiko Date, Tsutomu Masujima and Mitsuo Takayama
"Methyl vinyl ketone, a toxic ingredient in cigarette smoke extract, modifies glutathione in mouse melanoma cells"
Chem Pharm Bull, 62 (8): 772-778 (2014)
72）篠塚和正、和久田浩一、鳥取部直子、中村一基
「ATP を介したクロストーク-血管系における ATP を介したクロストーク-」
日本薬理学雑誌、１４３巻：２８３－２８８（２０１４）
71) Ayuko Sato, Noriko Yoshikawa, Erika Kubo, Mami Kakuda, Arisa Nishiuchi, Yoko Kimoto, Yuta Takahashi, Satomi Kagota, Kazumasa Shinozuka and Kazuki Nakamura
"Inhibitory effect of cordycepin on experimental hepatic metastasis of B16-F0 mouse melanoma cells"
in vivo, 27 (6): 729-732 (2013)
70) Satomi Kagota, Kana Maruyama, Yukari Tada, Hirokazu Wakuda, Kazuki Nakamura, Masaru Kunitomo and Kazumasa Shinozuka
"Abnormal amounts of intracellular calcium regulatory proteins in SHRSP.Z-Leprfa/IzmDmcr rats with metabolic syndrome and cardiac dysfunction"
Can J Physiol Pharmacol, 91 (2): 124-133 (2013)
69) Yuta Takahashi, Shizuyo Horiyama, Chie Honda, Kiyoko Suwa, Kazuki Nakamura, Masaru Kunitomo, Shuichi Shimma, Michisato Toyoda, Hirofumi Sato, Motohiro Shizuma and Mitsuo Takayama
"A chemical approach to searching for bioactive ingredients in cigarette smoke"
Chem Pharm Bull, 61 (1): 85-89 (2013)
68)Yuta Takahashi, Shizuyo Horiyama, Yoko Kimoto, Noriko Yoshikawa, Masaru Kunitomo, Satomi Kagota, Kazumasa Shinozuka and Kazuki Nakamura
"Inhibitory effect of cigarette smoke extract on experimental lung metastasis of mouse melanoma by suppressing tumor invasion"
Pharmacology and Pharmacy, 3 (3): 324-329 (2012)
67) Yoko Kubota, Keizo Umegaki, Naoko Tanaka, Satomi Kagota, Kazuki Nakamura, Masaru Kunitomo, Yasuo Watanabe and Kazumasa Shinozuka
"Effects of short-term Ginkgo biloba extract feeding on hypotensive action of nicardipine in rats"
Pharmacometrics, 82 (1/2): 29-34 (2012)
66) Erika Kubo, Ayuko Sato, Noriko Yoshikawa, Satomi Kagota, Kazumasa Shinozuka and Kazuki Nakamura
"Effect of Cordyceps sinensis on TIMP-1 secretion from mouse melanoma cell"
Cent Eur J Biol, 7 (1): 167-171 (2012)
65) Noriko Yoshikawa, Arisa Nishiuchi, Erika Kubo, Yu Yamaguchi, Masaru Kunitomo, Satomi Kagota, Kazumasa Shinozuka and Kazuki Nakamura
"Cordyceps sinensis acts as an adenosine A3 receptor agonist on mouse melanoma and lung carcinoma cells, and human fibrosarcoma and colon carcinoma cells"
Pharmacology and Pharmacy, 2 (4): 266-270 (2011)
64）Satomi Kagota, Yukari Tada, Namie Nejime, Kazuki Nakamura, Masaru Kunitomo and Kazumasa Shinozuka
"Telmisartan provides protection against development of impaired vasodilation independently of metabolic effects in SHRSP.Z-Lepr(fa)/IzmDmcr rats with metabolic syndrome"
Can J Physiol Pharmacol, 89 (5): 355-364 (2011)
63）Erika Kubo, Noriko Yoshikawa, Masaru Kunitomo, Satomi Kagota, Kazumasa Shinozuka and Kazuki Nakamura
"Inhibitory effect of Cordyceps sinensis on experimental hepatic metastasis of melanoma by suppressing tumor cell invasion"
Anticancer Res, 30 (9): 3429-3433 (2010)
62）Satomi Kagota, Kazuhito Fukushima, Keiji Umetani, Yukari Tada, Namie Nejime, Kazuki Nakamura, Hidezo Mori, Kazuro Sugimura, Masaru Kunitomo and Kazumasa Shinozuka
"Coronary vascular dysfunction promoted by oxidative-nitrative stress in SHRSP.Z-Leprfa/IzmDmcr rats with metabolic syndrome"
Clin Exp Pharmacol Physiol, 37 (11): 1035-1043 (2010)
61) Noriko Yoshikawa, Masaru Kunitomo, Satomi Kagota, Kazumasa Shinozuka and Kazuki Nakamura
"Inhibitory effect of cordycepin on hematogenic metastasis of B16-F1 mouse melanoma cells accelerated by adenosine-5’-diphosphate"
Anticancer Res, 29 (10): 3857-3860 (2009)
60) Masaru Kunitomo, Yu Yamaguchi, Satomi Kagota, Noriko Yoshikawa, Kazuki Nakamura and Kazumasa Shinozuka
"Biochemical evidence of atherosclerosis progression mediated by increased oxidative stress in apolipoprotein E-deficient
spontaneously hyperlipidemic mice exposed to chronic cigarette smoke"
J Pharmacol Sci, 110 (3): 354-361 (2009)
59) Satomi Kagota, Yukari Tada, Namie Nejime, Kazuki Nakamura, Masaru Kunitomo and Kazumasa Shinozuka
"Chronic production of peroxynitrite in the vascular wall impairs vasorelaxation function in SHR/NDmcr-cp rats, an animal model of metabolic syndrome"
J Pharmacol Sci, 109 (4): 556-564 (2009)
58）Namie Nejime, Satomi Kagota, Yukari Tada, Kazuki Nakamura, Michio Hashimoto, Masaru Kunitomo and Kazumasa Shinozuka
"Possible participation of chloride ion channels in ATP release from cancer cells in suspension"
Clin Exp Pharmacol Physiol, 36 (3): 278-282 (2009)
57) Noriko Yoshikawa, Shizuo Yamada, Chihiro Takeuchi, Satomi Kagota, Kazumasa Shinozuka, Masaru Kunitomo and Kazuki Nakamura
"Cordycepin (3’-deoxyadenosine) inhibits the growth of B16-BL6 mouse melanoma cells through the stimulation of adenosine A3 receptor
followed by glycogen synthase kinase-3β activation and cyclin D1 suppression"
Naunyn Schmiedebergs Arch Pharmacol, 377 (4-6): 591-595 (2008)
56）Namie Nejime, Naoko Tanaka, Ryoko Yoshihara, Satomi Kagota, Noriko Yoshikawa, Kazuki Nakamura, Masaru Kunitomo,
Michio Hashimoto and Kazumasa Shinozuka
"Effect of P2 receptor on the intracellular calcium increase by cancer cells in human umbilical vein endothelial cells"
Naunyn Schmiedebergs Arch Pharmacol, 377 (4-6): 429-436 (2008)
55) Yukari Tada, Satomi Kagota, Yoko Kubota, Namie Nejime, Kazuki Nakamura, Masaru Kunitomo and Kazumasa Shinozuka
"Long-term feeding of Ginkgo biloba extract impairs peripheral circulation and hepatic function in aged spontaneously hypertensive rats"
Biol Pharm Bull, 31 (1): 68-72 (2008)
54) Satomi Kagota, Yukari Tada, Yoko Kubota, Namie Nejime, Yu Yamaguchi, Kazuki Nakamura, Masaru Kunitomo and Kazumasa Shinozuka
"Peroxynitrite is involved in the dysfunction of vasorelaxation in SHR/NDmcr-cp rats, spontaneously hypertensive obese rats"
J Cardiovasc Pharmacol, 50 (6): 677-685 (2007)
53）Noriko Yoshikawa, Kazuki Nakamura, Yu Yamaguchi, Satomi Kagota, Kazumasa Shinozuka and Masaru Kunitomo
"Cordycepin and Cordyceps sinensis reduce the growth of human promyelocytic leukemia cells through the Wnt signaling pathway"
Clin Exp Pharmacol Physiol, 34: S61-S63（2007）
52）Tsugumi Morikawa, Naoko Tanaka, Yoko Kubota, Hideya Mizuno, Kazuki Nakamura, Masaru Kunitomo and Kazumasa Shinozuka
"ATP modulates the release of noradrenalin through two different prejunctional receptors on the adrenergic nerves of rat prostate"
Clin Exp Pharmacol Physiol, 34: 601-605 (2007)
51）Noriko Yoshikawa, Kazuki Nakamura, Yu Yamaguchi, Satomi Kagota, Kazumasa Shinozuka and Masaru Kunitomo
"Reinforcement of Antitumor Effect of Cordyceps Sinensis by 2'-Deoxycoformycin, an Adenosine Deaminase Inhibitor"
in vivo, 21 (2): 291-296 (2007)
50) Satomi Kagota, Yoko Kubota, Namie Nejime, Kazuki Nakamura, Masaru Kunitomo and Kazumasa Shinozuka
"Impaired effect of salt loading on nitric oxide-mediated relaxation in aortas from stroke-prone spontaneously hypertensive rats"
Clin Exp Pharmacol Physiol, 34: 48-54 (2007)
49) Yu Yamaguchi, Kotaro Yamada, Noriko Yoshikawa, Kazuki Nakamura, Jun Haginaka and Masaru Kunitomo
"Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome"
Life Sciences, 79(26): 2474-2479 (2006)
48）Yoko Kubota, Keizo Umegaki, Satomi Kagota, Naoko Tanaka, Kazuki Nakamura, Masaru Kunitomo and Kazumasa Shinozuka
"Evaluation of blood pressure measured by tail-cuff methods (without heating) in spontaneously hypertensive rats"
Biol Pharm Bull, 29(8): 1756-1758 (2006)
47）Yu Yamaguchi, Noriko Yoshikawa, Satomi Kagota, Kazuki Nakamura, Jun Haginaka and Masaru Kunitomo
"Elevated circulating levels of markers of oxidative-nitrative stress and inflammation in a genetic rat model of metabolic syndrome"
Nitric Oxide, 15(4): 380-386 (2006)
46）Tanaka N, Nejime N, Kagota S, Kubota Y, Yudo K, Nakamura K, Kunitomo M, Takahashi K, Hashimoto M and Shinozuka K
"ATP participates in the regulation of microvessel permeability"
J Pharm Pharmacol, 58(4): 481-487 (2006)
45）Kazuki Nakamura, Noriko Yoshikawa, Yu Yamaguchi, Satomi Kagota, Kazumasa Shinozuka and Masaru Kunitomo
"Antitumor effect of cordycepin (3'-deoxyadenosine) on mouse melanoma and lung carcinoma cells involves adenosine A3 receptor stimulation"
Anticancer Res, 26(1A): 43-47 (2006)
44）Yoko Kubota, Naoko Tanaka, Satomi Kagota, Kazuki Nakamura, Masaru Kunitomo, Keizo Umegaki and Kazumasa Shinozuka
"Effects of Ginkgo biloba extract feeding on salt-induced hypertensive Dahl rats"
Biol Pharm Bull, 29(2): 266-269 (2006)
43）Yoko Kubota, Naoko Tanaka, Satomi Kagota, Kazuki Nakamura, Masaru Kunitomo, Keizo Umegaki and Kazumasa Shinozuka
"Effects of Ginkgo biloba extract on blood pressure and vascular endothelial response by acetycholine in spontaneously hypertensive rats"
J Pharm Pharmacol, 58(2): 243-249 (2006)
42） Satomi Kagota, Yu Yamaguchi, Naoko Tanaka, Yoko Kubota, Kyoko Kobayashi, Namie Nejime, Kazuki Nakamura,
Masaru Kunitomo and Kazumasa Shinozuka
"Disturbances in nitric oxide/cyclic guanosine monophosphate system in SHR/NDmcr-cp rats, a model of metabolic syndrome"
Life Sci, 78(11): 1187-1196 (2006)
41）Tanaka N, Nejime N, Kubota Y, Kagota S, Yudo K, Nakamura K, Kunitomo M, Takahashi K, Hashimoto M and Shinozuka K
"Myosin light chain kinase and Rho-kinase participate in P2Y receptor-mediated acceleration of permeability through the endothelial cell layer"
J Pharm Pharmacol, 57(3): 335-340 (2005)
40）Kazuki Nakamura, Keiko Konoha, Noriko Yoshikawa, Yu Yamaguchi, Satomi Kagota,Kazumasa Shinozuka and Masaru Kunitomo
"Effect of cordycepin (3'-deoxyadenosine) on hematogenic lung metastatic model mice"
in vivo, 19: 137-142 (2005)
39）Naoko Tanaka, Namie Nejime, Satomi Kagota, Yoko Kubota, Kazuki Nakamura, Masaru Kunitomo, Michio Hashimoto,
Ryuichi Yamamoto and Kazumasa Shinozuka
"Dysfunction of purinergic regulation of sympathetic neurotransmission in SHR/NDMCR-CP (SHR-CP) rat"
Clin Exp Pharmacol Physiol, 31: S60-S61 (2004)
38）Yoko Kubota, Keizo Umegaki, Kyoko Kobayashi, Naoko Tanaka, Satomi Kagota, Kazuki Nakamura,
Masaru Kunitomo and Kazumasa Shinozuka
"Anti-hypertensive effects of brazilian propolis in spontaneously hypertensive rats"
Clin Exp Pharmacol Physiol, 31: S29-S30 (2004)
37） Satomi Kagota, Naoko Tanaka, Yoko Kubota, Yu Yamaguchi, Kazuki Nakamura, Masaru Kunitomo and Kazumasa Shinozuka
"Characteristics of vasorelaxation responses in a rat model of metabolic syndrome"
Clin Exp Pharmacol Physiol, 31: S54-S56 (2004)
36）Noriko Yoshikawa, Kazuki Nakamura, Yu Yamaguchi, Satomi Kagota, Kazumasa Shinozuka and Masaru Kunitomo
"Antitumour activity of cordycepin in mice"
Clin Exp Pharmacol Physiol, 31: S51-S53 (2004)
35）窪田洋子、小林恭子、田中直子、籠田智美、中村一基、国友勝、梅垣敬三、篠塚和正
「老齢ラットの循環機能に対するイチョウ葉エキス 4 週間反復摂取の影響」
日本食品化学学会誌、１１巻２号：８１-８５（２００４）
34）Naoko Tanaka, Kumiko Kawasaki, Namie Nejime, Yoko Kubota, Kazuki Nakamura, Masaru Kunitomo, Koichi Takahashi,
Michio Hashimoto and Kazumasa Shinozuka
"P2Y receptor-mediated Ca２＋ signaling increases human vascular endothelial cell permeability"
J Pharmacol Sci, 95 (2): 174-180 (2004)
33）Satomi Kagota, Yu Yamaguchi, Kazuki Nakamura, Kazumasa Shinozuka, Masaru Kunitomo
"Sustaining excessive nitric oxide upregulates protein expression of nitric oxide synthase via soluble guanylyl cyclase: An in vivo study in rats"
J Cardiovasc Pharmacol, 44 (1): 42-49 (2004)
32）Satomi Kagota, Yu Yamaguchi, Kazuki Nakamura, Kazumasa Shinozuka, Masaru Kunitomo
"Chronic nitric oxide exposure alters the balance between endothelium-derived relaxing factors released from
rat renal arteries: prevention by treatment with NOX-100, a NO scavenger"
Life Sciences, 74 (22): 2757-2767 (2004)
31）Yoko Kubota, Kyoko Kobayashi, Naoko Tanaka, Kazuki Nakamura, Masaru Kunitomo, Keizo Umegaki and Kazumasa Shinozuka
"Pretreatment with Ginkgo biloba extract weakens the hypnosis action of phenobarbitaland its plasma concentration in rats"
J Pharm Pharmacol, 56 (3): 401-405 (2004)
30）Yoko Kubota, Kyoko Kobayashi, Naoko Tanaka, Kazuki Nakamura, Masaru Kunitomo, Keizo Umegaki and Kazumasa Shinozuka
"Interaction of Ginkgo Biloba Extract (GBE) with Hypotensive Agent, Nicardipine, in Rats"
in vivo, 17: 409-412 (2003)
29) Kazuki Nakamura, Keiko Konoha, Yu Yamaguchi, Satomi Kagota, Kazumasa Shinozuka and Masaru Kunitomo
"Combined effect of Cordyceps sinensis and methotrexate on hematogenic lung metastasis in mice"
Receptors and Channels, 9 (5): 329-334 (2003)
28) Kazuki Nakamura, Noriko Yoshikawa, Yu Yamaguchi, Satomi Kagota, Kazumasa Shinozuka and Masaru Kunitomo
"Effect of PKC412, an inhibitor of protein kinase C, on spontaneous metastatic model mice"
Anticancer Research, 23 (2B): 1395-1400 (2003)
27）Naoko Tanaka, Kumiko Kawasaki, Yoko Kubota, Kazuki Nakamura, Michio Hashimoto, Masaru Kunitomo and Kazumasa Shinozuka
"P2Y-receptor regulates size of endothelial cells in an intracellular Ca２＋ dependent manner"
Life Sciences, 72 (13): 1445-1453 (2003)
26）Noriko Yoshikawa, Kazuki Nakamura, Yu Yamaguchi, Satomi Kagota, Kazumasa Shinozuka and Masaru Kunitomo
"Effect of PKC412, a selective inhibitor of protein kinase C, on lung metastasis in mice injected with B16 melanoma cells"
Life Sciences, 72 (12): 1377-1387 (2003)
25）窪田洋子、梅垣敬三、田中直子、小林恭子、中村一基、国友勝、篠塚和正
「ラット循環機能に対するプロポリスの4週間反復摂取の影響」
日本食品化学学会誌、９巻２号：５４-５９（２００２）
24）Kazumasa Shinozuka, Keizo Umegaki, Yoko Kubota, Naoko Tanaka, Hideya Mizuno, Jun Yamauchi,
Kazuki Nakamura and Masaru Kunitomo
"Feeding of Ginkgo biloba extract (GBE) enhances gene expression of hepatic cytochrome P-450 and attenuates
the hypotensive effect of nicardipine in rats"
Life Sciences, 70 (23): 2783-2792 (2002)
23) Satomi Kagota, Akiko Tamashiro, Yu Yamaguchi, Kazuki Nakamura and Masaru Kunitomo
"High salt intake inpairs vascular nitric oxide/cyclic guanosine monophosphate systemin spontaneously hypertensive rats"
J Pharmacol Exp Ther, 302 (1):344-51 (2002)
22）Yoko Kubota, Keizo Umegaki, Naoko Tanaka, Hideya Mizuno, Kazuki Nakamura, Masaru Kunitomo and Kazumasa Shinozuka
"Safety of dietary supplements: Chronotropic and inotropic effects on isolated rat atria"
Biol Pharm Bull, 25: 197-200 (2002)
21）Kazumasa Shinozuka, Hideya Mizuno, Kazuki Nakamura and Masaru Kunitomo
"Purinergic modulation of vascular sympathetic neurotransmission"
Jpn J Pharmacol, 88: 19-25 (2002)
20) Kazuki Nakamura, Noriko Yoshikawa, Yu Yamaguchi, Satomi Kagota, Kazumasa Shinozuka and Masaru Kunitomo
"Characterization of mouse melanoma cell lines by their mortal malignancy using an experimental metastatic model"
Life Sciences, 70 (7): 791-798 (2002)
19）Noriko Yoshikawa, Kazuki Nakamura, Yu Yamaguchi, Satomi Kagota, Kazumasa Shinozuka and Masaru Kunitomo
"Suitable Indices for evaluating the intensity of tumor metastasis in a mouse experimental metastatic model"
in vivo, 15 (6): 485-488 (2001)
18）Yoko Kubota, Naoko Tanaka, Keizo Umegaki, Hiroyuki Takenaka, Hideya Mizuno, Kazuki Nakamura,
Kazumasa Shinozuka and Masaru Kunitomo
"Ginkgo biloba extract-induced relaxation of rat aorta is associated with increase inendothelial intracellular calcium level"
Life Sciences, 69: 2327-2336 (2001)
17）窪田洋子、梅垣敬三、田中直子、水野英哉、中村一基、国友勝、篠塚和正
「ラット循環機能に対する各種健康食品の4週間反復投与の影響」
日本食品化学学会誌、８巻３号：１４９-１５４（２００１）
16) Satomi Kagota, Akiko Tamashiro, Yu Yamaguchi, Reiko Sugiura, Takayoshi Kuno, Kazuki Nakamura and Masaru Kunitomo
"Downregulation of vascular soluble guanylate cyclase induced by high salt intake in spontaneously hypertensive rats"
British Journal of Pharmacology, 134:737-44 (2001)
15) Kazumasa Shinozuka, Naoko Tanaka, Kumiko Kawasaki, Hideya Mizuno, Yoko Kubota, Kazuki Nakamura,
Michio Hashimoto and Masaru Kunitomo
"Participation of ATP in cell volume regulation in the endothelium after hypotonic stress"
Clin Exp Pharmacol Physiol, 28: 799-803 (2001)
14) Kagota S, Yamaguchi Y, Nakamura K, Sugiura T, Waku K and Kunitomo M
"2-Arachidonoylglycerol, a candidate of endothelium-derived hyperpolarizing factor"
Eur J Pharmacol, 415: 233-238 (2001)
13) Kazumasa Shinozuka, Yoshie Tanioka, Young Mi Kwon, Naoko Tanaka, Yoko Kubota, Kazuki Nakamura and Masaru Kunitomo
"Characterization of prejunctional prinoceptors inhibiting noradrenaline release in rat mesenteric arteries"
Jpn J Pharmacol, 85: 41-46 (2001)
12) Yu Yamaguchi, Satomi Kagota, Kazuki Nakamura, Kazumasa Shinozuka and Masaru Kunitomo
"Inhibitory effects of water extracts from fruiting bodies of cultured cordyceps sinensis on raised serum lipid peroxide levels
and aortic cholesterol deposition in atherosclerotic mice"
Phytotherapy Research, 14: 650-652 (2000)
11) Yu Yamaguchi, Satomi Kagota, Kazuki Nakamura, Kazumasa Shinozuka and Masaru Kunitomo
"Antioxidant activity of the extracts from fruiting bodies of cultured cordyceps sinensis"
Phytotherapy Research, 14: 647-649 (2000)
10) 中村一基、篠塚和正、国友勝
「Cキナーゼ阻害剤によるP53蛋白リン酸化を介した癌細胞機能抑制」
薬学雑誌、Vol.120, No.12: 1387-1394 (2000)
[平成11年度日本薬学会近畿支部奨励賞受賞記念総説]
9) Satomi Kagota, Yu Yamaguchi, Kazuki Nakamura and Masaru Kunitomo
"Functional evidence for anti-oxidant action of fluvastatin on low-density lipoprotein using isolated macrophages and aorta"
Clinical and Experimental Pharmacology and Physiology, 27: 401-405 (2000)
8) Satomi Kagota, Yu Yamaguchi, Kazuki Nakamura and Masaru Kunitomo
"Altered endothelium-dependent responsiveness in the aortas and renal arteries of otsuka long-evans
tokushima fatty (OLETF) rats, a model of non-insulin-dependent diabetes mellitus"
General Pharmacology, 34 (3): 201-209 (2000)
7) Kazuki Nakamura, Yi Sun, Yoshihiro Yokoyama, Douglas Ferris, Neeta Singh, Tomio Ichikawa,
Kazumasa Shinozuka, Masaru Kunitomo and Nancy Colburn
"Phosphorylation status and function of p53 are inversely related to protein kinase C activation"
Anticancer Research, 20 (1A): 1-5 (2000)
6) Satomi Kagota, Yu Yamaguchi, Kazuki Nakamura and Masaru Kunitomo
"Characterization of nitric oxide- and prostaglandin-independent relaxation in response to acetylcholine in rabbit renal artery"
Clinical and Experimental Pharmacology and Physiology, 26: 790-796 (1999)
5) Satomi Kagota, Akiko Tamashiro, Yu Yamaguchi, Kazuki Nakamura and Masaru Kunitomo
"Excessive Salt or Cholesterol Intake Alters the Balance Among Endothelium-Derived Factors Released from
Renal Arteries in Spontaneously Hypertensive Rats"
Journal of Cardiovascular Pharmacology, 34: 533-539 (1999)
4) 権寧美、籠田智美、山口優、中村一基、篠塚和正、国友勝
「過酸化ベンゾイルの循環器系に及ぼす影響」
日本食品化学学会誌、６巻１号：１-７（１９９９）
3) Young Mi Kwon, Kazumasa Shinozuka, Satomi Kagota, Yu Yamaguchi, Kazuki Nakamura and Masaru Kunitomo
"Both extracellular ATP and shear stress regulate the release of nitric oxide in rat caudal artery."
Clinical and Experimental Pharmacology and Physiology, 26: 465-469 (1999)
2) Kazuki Nakamura, Yu Yamaguchi, Satomi Kagota, Kazumasa Shinozuka and Masaru Kunitomo
"Activation of In Vivo Kupffer Cell Function by Oral Administration of Cordyceps Sinensis in Rats."
Jpn J Pharmacol, 79 (4): 505-508 (1999)
1) Kazuki Nakamura, Yu Yamaguchi, Satomi Kagota, Young Mi Kwon, Kazumasa Shinozuka and Masaru Kunitomo
"Inhibitory Effect of Cordyceps Sinensis on Spontaneous Liver Metastasis of Lewis Lung Carcinoma
and B16 Melanoma Cells in Syngeneic Mice."
Jpn J Pharmacol, 79 (3): 335-341 (1999)