研究室から発表された成果の一覧です。


免疫生物学教室

原著論文

2013

Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1receptor paracrine axis.
Taketomi, Y., Ueno, N., Kojima, T., Sato, H., Murase, R., Yamamoto, K., Tanaka, S., Sakanaka, M., Nakamura, M., Nishito, Y., Kawana, M., Kambe, N., Ikeda, K., Taguchi, R., Nakamizo, S., Kabashima, K., Gelb, MH., Arita, M., Yokomizo, T., Nakamura, M., Watanabe, K., Hirai, H., Nakamura, M., Okayama, Y., Ra, C., Aritake, K., Urade, Y., Morimoto, K., Sugimoto, Y., Shimizu, T., Narumiya, S., Hara, S., Murakami, M. Nat Immunol. in press

2012

Caffeic acid phenethyl ester suppresses the production of pro-inflammatory cytokines in hypertrophic adipocytes through lipopolysaccharide-stimulated macrophages.
Juman, S., Yasui, N., Ikeda, K., Ueda, A., Sakanaka, M., Negishi, H., Miki, T. Biol. Pharm. Bull., 35(11):1941-6

Restriction of mast cell proliferation through hyaluronan synthesis by co-cultured fibroblasts.
Takano, H., Furuta, K., Yamashita, K., Sakanaka, M., Itano, N., Gohda, E., Nakayama, K., Kimata, K., Sugimoto, Y., Ichikawa, A., and Tanaka, S. Biol. Pharm. Bull., 35(3):408-412

2011

Repeated and long-term treatment with physiological concentrations of resveratrol promotes NO production in vascular endothelial cells.
Takahashi, S., Nakashima, Y. Br J Nutr. 1-7

Vascular Endothelial Growth Factor (VEGF), VEGF Receptors and Their Inhibitors for Antiangiogenic Tumor Therapy.
Takahashi, S. Biol. Pharm. Bull., 34, 1785-1788

2010

Impaired activation of mast cells upon IgE-mediated antigen stimulation in a stroke-prone spontaneously hyperensive rat strain, SHRSP.Z.
Sakanaka, M., Furuta, K., Ichikawa, A., and Tanaka, S. Immunol. Lett. 128, 74-79

2009

Interleukin-4-mediated suppression of histamine synthesis in a murine mast cell line, BNu-2cl3.
Sato, N., Tanaka, S.*, Matsuura, J., Takasu, Y., and Ichikawa, A. Biol. Pharm. Bull. 32(10):1800-2

Characterization of gene expression profiles for different types of mast cells pooled from mouse stomach subregions by an RNA amplification method.
Tsuchiya, S., Tachida, Y., Segi-Nishida, E., Okuno, Y., Tamba, S., Tsujimoto, G., Tanaka, S., and Sugimoto, Y. BMC Genomics 10, 35

Involvement of CD44 in mast cell proliferation during terminal differentiation.
Takano, H., Nakazawa, S., Shirata, N., Tamba, S., Furuta, K., Tsuchiya, S., Morimoto, K., Itano, N., Irie, A., Kimata, K., Nakayama, K., Sugimoto, Y., and Tanaka, S. Lab. Invest. 89, 446-455

2008

Essential role of EP3 subtype in prostaglandin E2-induced adhesion of mouse cultured and peritoneal mast cells to the Arg-Gly-Asp-enriched matrix.
Sakanaka, M., Tanaka, S.*, Sugimoto, Y., and Ichikawa A. Am. J. Physiol.-Cell Physiol. 295, C1427-C1433

Establishment of the culture model system that reflects the process of terminal differentiation of connective tissue-type mast cells.
Takano, H., Nakazawa, S., Okuno, Y., Shirata, N., Tsuchiya, S., Kainoh, T., Takamatsu, S., Furuta, K., Taketomi, Y., Naito, Y., Takematsu, H., Kozutsumi, Y., Tsujimoto, G., Murakami, M., Kudo, I., Ichikawa, A., Nakayama, K., Sugimoto, Y., and Tanaka, S. FEBS Lett. 582, 1444-1450

PGE2-receptor subtype EP4-dependent adherance of mastocytoma P-815 cells to matrix components in subcutaneous tissues overlaying inside surface of air pouch cavity in CDF1 mouse.
Kataoka, H., Sakanaka, M., Semma, M., Yamamoto, T., Hirota, S., Tanaka, S.*, and Ichikawa A. Inflamm. Res. 57, 362-366

2007

Development of eosinophilic conjunctival inflammation at late-phase reaction in mast cell-deficient mice.
Ueta, M., Nakamura, T., Tanaka, S., Kojima, K., and Kinoshita, S. J. Allergy Clin. Immunol. 120, 476-478

Impaired mast cell maturation and degranulation and attenuated allergic responses in NDRG1-deficient mice.
Taketomi, Y., Sunaga, K., Tanaka, S., Nakamura, M., Arata, S., Okuda, T., Moon, T., Chang, H., Sugimoto, Y., Kokame, K., Miyata, T., Murakami, M., and Kudo, I. J. Immunol. 178, 7042-53

Activation of histidine decarboxylase through post-translational cleavage by caspase-9 in a mouse mastocytoma P-815.
Furuta, K., Nakayama, K., Sugimoto, Y., Ichikawa, A., and Tanaka, S. J. Biol. Chem. 282, 13438-13446

2006

Membrane orientation of the precursor 74-kDa form of L-histidine decarboxylase.
Furuta, K., Ichikawa, A., Nakayama, K., and Tanaka, S. Inflamm. Res. 55, 185-191

総説

2006

Immune regulatory roles of histamine produced by leukocytes. (Review)
Tanaka, S., and Ichikawa, A. J. Pharmacol. Sci. 101, 19-23

和文総説

2007

マスト細胞の成熟とヒアルロン酸
田中 智之 表面 45巻、312-321

IgEを介するマスト細胞活性化の多様性
特集「マスト細胞の活性化をめぐって」
田中 智之 臨床免疫・アレルギー科 47巻、421-426

2006

単量体IgEによるマスト細胞の活性化
特集「アレルギー疾患におけるマスト細胞の位置づけ」
田中 智之 アレルギー・免疫、13巻、50-56

マスト細胞におけるIgEを介したヒスタミン合成の誘導機構
特集「アレルギー性炎症反応におけるヒスタミンの役割と抗ヒスタミン薬」
田中 智之 アレルギー科、21巻、438-444

その他

2011

日本薬学会誌ファルマシア トピックス生物系「慢性皮膚炎におけるマウスCCL8の機能」 阪中麻利子

2008

わかりやすい免疫学 市川厚・田中智之(編)廣川書店 (目次